Detailed information NTG1139260

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQM61_RS00805
• Genome accession: NZ_LS483379
• Coordinates: 118997..119431 (+)
• Length: 144 a.a.
• NCBI ID: WP_002992738.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10874
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 113997..124431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM61_RS00775 (NCTC10874_00157)	-	115666..116031 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQM61_RS00780 (NCTC10874_00158)	comYA	116124..117062 (+)	939	WP_002993471.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM61_RS00785 (NCTC10874_00159)	comYB	116998..118032 (+)	1035	WP_225793059.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM61_RS00790 (NCTC10874_00160)	comYC	118034..118360 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM61_RS00795 (NCTC10874_00161)	comGD	118335..118763 (+)	429	WP_023605232.1	competence type IV pilus minor pilin ComGD	-
DQM61_RS00800 (NCTC10874_00162)	comGE	118720..119004 (+)	285	WP_011284422.1	competence type IV pilus minor pilin ComGE	-
DQM61_RS00805 (NCTC10874_00163)	comYF	118997..119431 (+)	435	WP_002992738.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM61_RS00810 (NCTC10874_00164)	comGG	119415..119741 (+)	327	WP_002992739.1	competence type IV pilus minor pilin ComGG	-
DQM61_RS00815 (NCTC10874_00165)	comYH	119839..120792 (+)	954	WP_023610092.1	class I SAM-dependent methyltransferase	Machinery gene
DQM61_RS00820 (NCTC10874_00166)	-	120851..122047 (+)	1197	WP_002992742.1	acetate kinase	-
DQM61_RS00825	-	122234..122542 (+)	309	WP_032467031.1	hypothetical protein	-
DQM61_RS00830 (NCTC10874_00167)	proC	122625..123395 (-)	771	WP_002992745.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16645.27 Da
• Isoelectric Point: 10.2526

>NTDB_id=1139260 DQM61_RS00805 WP_002992738.1 118997..119431(+) (comYF) [Streptococcus pyogenes strain NCTC10874]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1139260 DQM61_RS00805 WP_002992738.1 118997..119431(+) (comYF) [Streptococcus pyogenes strain NCTC10874]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396