Detailed information NTG0113897

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: Q426_RS04080
• Genome accession: NZ_CP006770
• Coordinates: 867167..867904 (-)
• Length: 245 a.a.
• NCBI ID: WP_014622844.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus CY
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 862167..872904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q426_RS10025	-	862861..863142 (-)	282	WP_080004977.1	lactococcin 972 family bacteriocin	-
Q426_RS04060 (Q426_04335)	-	864012..864242 (-)	231	WP_012515596.1	Blp family class II bacteriocin	-
Q426_RS04065 (Q426_04340)	-	864504..865667 (-)	1164	WP_014622845.1	ABC transporter permease subunit	-
Q426_RS04070 (Q426_04345)	-	865673..866527 (-)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
Q426_RS04075 (Q426_04350)	-	866594..866794 (-)	201	WP_012679509.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
Q426_RS04080 (Q426_04355)	comE/blpR	867167..867904 (-)	738	WP_014622844.1	response regulator transcription factor	Regulator
Q426_RS04085 (Q426_04360)	-	868667..868972 (-)	306	WP_012677981.1	AraC family ligand binding domain-containing protein	-
Q426_RS04090 (Q426_04365)	-	868974..869312 (-)	339	WP_014622843.1	cupin domain-containing protein	-
Q426_RS04095 (Q426_04370)	-	869340..870095 (-)	756	WP_014622842.1	class I SAM-dependent methyltransferase	-
Q426_RS04100 (Q426_04375)	-	870355..870810 (+)	456	WP_014622841.1	DUF1836 domain-containing protein	-
Q426_RS04105 (Q426_04380)	trhA	870794..871444 (+)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
Q426_RS04110 (Q426_04385)	-	871554..872459 (+)	906	WP_012677986.1	diacylglycerol/lipid kinase family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28903.28 Da
• Isoelectric Point: 8.2679

>NTDB_id=113897 Q426_RS04080 WP_014622844.1 867167..867904(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus CY]
MNIFILEDDLGQQFRLQMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHRLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKLKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=113897 Q426_RS04080 WP_014622844.1 867167..867904(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus CY]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTCAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATTGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAGGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAACGGGCAGTCTTGCATGGTTTCAAGACTAAAACTGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (16-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.306	98.776	0.527
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367