Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DQM56_RS07695 Genome accession   NZ_LS483368
Coordinates   1613015..1613764 (-) Length   249 a.a.
NCBI ID   WP_111690344.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6176     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1608015..1618764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM56_RS07680 (NCTC6176_01560) - 1609970..1611328 (+) 1359 WP_111710737.1 bacteriocin secretion accessory protein -
  DQM56_RS07685 (NCTC6176_01561) - 1611428..1611559 (+) 132 WP_012677513.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQM56_RS07690 (NCTC6176_01562) - 1611681..1613015 (-) 1335 WP_111710738.1 sensor histidine kinase -
  DQM56_RS07695 (NCTC6176_01563) comE/blpR 1613015..1613764 (-) 750 WP_111690344.1 LytR/AlgR family response regulator transcription factor Regulator
  DQM56_RS07700 (NCTC6176_01564) - 1614400..1614594 (-) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DQM56_RS07705 (NCTC6176_01565) - 1614611..1614868 (-) 258 WP_038674051.1 Blp family class II bacteriocin -
  DQM56_RS07710 (NCTC6176_01566) rlmD 1615189..1616556 (-) 1368 WP_111710739.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  DQM56_RS07715 (NCTC6176_01567) - 1616553..1617521 (-) 969 WP_111710740.1 helix-hairpin-helix domain-containing protein -
  DQM56_RS07720 (NCTC6176_01568) - 1617964..1618149 (-) 186 WP_111710741.1 hypothetical protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29217.65 Da        Isoelectric Point: 8.4602

>NTDB_id=1138910 DQM56_RS07695 WP_111690344.1 1613015..1613764(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRSHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1138910 DQM56_RS07695 WP_111690344.1 1613015..1613764(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGTCTCACCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTTTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

100

0.522
  comE/comE1 Streptococcus equinus JB1

40.586

95.984

0.39
  comE/comE2 Streptococcus equinus JB1

36.29

99.598

0.361

Multiple sequence alignment