Detailed information NTG1138898

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQM56_RS05050
• Genome accession: NZ_LS483368
• Coordinates: 1053142..1053879 (+)
• Length: 245 a.a.
• NCBI ID: WP_043052135.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1048142..1058879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS05020 (NCTC6176_01017)	-	1048583..1049488 (-)	906	WP_012515585.1	diacylglycerol/lipid kinase family protein	-
DQM56_RS05025 (NCTC6176_01018)	trhA	1049598..1050248 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
DQM56_RS05030 (NCTC6176_01019)	-	1050232..1050687 (-)	456	WP_012515587.1	DUF1836 domain-containing protein	-
DQM56_RS05035 (NCTC6176_01020)	-	1050947..1051702 (+)	756	WP_012515588.1	class I SAM-dependent methyltransferase	-
DQM56_RS05040	-	1051730..1052068 (+)	339	Protein_959	cupin domain-containing protein	-
DQM56_RS05045 (NCTC6176_01022)	-	1052070..1052375 (+)	306	WP_012515590.1	hypothetical protein	-
DQM56_RS05050 (NCTC6176_01023)	comE/blpR	1053142..1053879 (+)	738	WP_043052135.1	response regulator transcription factor	Regulator
DQM56_RS05055 (NCTC6176_01024)	-	1054252..1054452 (+)	201	WP_012679509.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQM56_RS05060 (NCTC6176_01025)	-	1054519..1055373 (+)	855	WP_111710558.1	ABC transporter ATP-binding protein	-
DQM56_RS05065 (NCTC6176_01026)	-	1055379..1056542 (+)	1164	WP_111710559.1	ABC transporter permease subunit	-
DQM56_RS05070 (NCTC6176_01027)	-	1056804..1057034 (+)	231	WP_012515596.1	Blp family class II bacteriocin	-
DQM56_RS05075 (NCTC6176_01028)	-	1057823..1058674 (+)	852	WP_111710560.1	thioredoxin family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28920.36 Da
• Isoelectric Point: 7.8796

>NTDB_id=1138898 DQM56_RS05050 WP_043052135.1 1053142..1053879(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=1138898 DQM56_RS05050 WP_043052135.1 1053142..1053879(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTAGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATATTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTTATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	37.295	99.592	0.371