Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   Q426_RS01140 Genome accession   NZ_CP006770
Coordinates   234760..235509 (+) Length   249 a.a.
NCBI ID   WP_014623345.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus CY     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 229760..240509
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q426_RS01115 (Q426_01170) recX 230166..230942 (-) 777 WP_012516130.1 recombination regulator RecX -
  Q426_RS01120 (Q426_01175) - 231006..231974 (+) 969 WP_012516123.1 helix-hairpin-helix domain-containing protein -
  Q426_RS01125 (Q426_01180) rlmD 231971..233338 (+) 1368 WP_014623348.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  Q426_RS01130 (Q426_01185) - 233659..233916 (+) 258 WP_038674051.1 Blp family class II bacteriocin -
  Q426_RS01135 (Q426_01190) - 233933..234127 (+) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  Q426_RS01140 (Q426_01195) comE/blpR 234760..235509 (+) 750 WP_014623345.1 LytR/AlgR family response regulator transcription factor Regulator
  Q426_RS10675 (Q426_01200) - 235509..236843 (+) 1335 WP_038674055.1 sensor histidine kinase -
  Q426_RS01150 (Q426_01205) - 236962..237096 (-) 135 WP_014623342.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  Q426_RS01155 (Q426_01210) - 237196..238554 (-) 1359 WP_038674057.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29231.68 Da        Isoelectric Point: 8.4602

>NTDB_id=113886 Q426_RS01140 WP_014623345.1 234760..235509(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus CY]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRSHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQIQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=113886 Q426_RS01140 WP_014623345.1 234760..235509(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus CY]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGTCTCACCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTTTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGATACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

100

0.522
  comE/comE1 Streptococcus equinus JB1

41.004

95.984

0.394
  comE/comE2 Streptococcus equinus JB1

36.694

99.598

0.365

Multiple sequence alignment