Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQM53_RS05790 Genome accession   NZ_LS483361
Coordinates   1132670..1133980 (-) Length   436 a.a.
NCBI ID   WP_111716507.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1127670..1138980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM53_RS05760 (NCTC6179_01188) - 1128104..1128493 (-) 390 WP_022554672.1 cytidine deaminase -
  DQM53_RS05765 (NCTC6179_01189) deoC 1128480..1129142 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  DQM53_RS05770 (NCTC6179_01190) - 1129158..1130435 (-) 1278 WP_111716503.1 pyrimidine-nucleoside phosphorylase -
  DQM53_RS05775 (NCTC6179_01191) - 1130422..1131021 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  DQM53_RS05780 (NCTC6179_01192) coaA 1131290..1132210 (+) 921 WP_111716505.1 type I pantothenate kinase -
  DQM53_RS05785 (NCTC6179_01193) rpsT 1132264..1132512 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  DQM53_RS05790 (NCTC6179_01194) ciaH 1132670..1133980 (-) 1311 WP_111716507.1 HAMP domain-containing sensor histidine kinase Regulator
  DQM53_RS05795 (NCTC6179_01195) ciaR 1133973..1134647 (-) 675 WP_111716510.1 response regulator transcription factor Regulator
  DQM53_RS05800 (NCTC6179_01196) - 1134851..1137388 (-) 2538 WP_111716513.1 M1 family metallopeptidase -
  DQM53_RS05805 (NCTC6179_01197) phoU 1137588..1138241 (-) 654 WP_111716515.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49895.46 Da        Isoelectric Point: 7.5498

>NTDB_id=1138529 DQM53_RS05790 WP_111716507.1 1132670..1133980(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLMNFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILIMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLSLAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1138529 DQM53_RS05790 WP_111716507.1 1132670..1133980(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCTAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACCACTAGCCTGATGAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATTATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGTCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCCCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCGAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGAGATGACGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGATAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCAATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGTCTTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGAAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.352

100

0.585
  ciaH Streptococcus pneumoniae Rx1

51.598

100

0.518
  ciaH Streptococcus pneumoniae D39

51.598

100

0.518
  ciaH Streptococcus pneumoniae R6

51.598

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.598

100

0.518

Multiple sequence alignment