Detailed information NTG1138480

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM47_RS07525
• Genome accession: NZ_LS483360
• Coordinates: 1457475..1458476 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC10876
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1452475..1463476

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM47_RS07510 (NCTC10876_01500)	thrS	1452645..1454588 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
DQM47_RS07515 (NCTC10876_01502)	-	1455010..1456344 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
DQM47_RS07520 (NCTC10876_01503)	-	1456346..1457344 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM47_RS07525 (NCTC10876_01504)	ccpA	1457475..1458476 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM47_RS07530 (NCTC10876_01505)	-	1458650..1459735 (+)	1086	WP_085577322.1	M24 family metallopeptidase	-
DQM47_RS07535 (NCTC10876_01506)	-	1459784..1460449 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM47_RS07540 (NCTC10876_01507)	-	1460460..1460837 (+)	378	WP_002985686.1	VOC family protein	-
DQM47_RS07545 (NCTC10876_01508)	-	1460982..1461908 (+)	927	WP_002985688.1	glycosyltransferase family 2 protein	-
DQM47_RS07550 (NCTC10876_01509)	-	1462119..1462802 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1138480 DQM47_RS07525 WP_002985680.1 1457475..1458476(-) (ccpA) [Streptococcus pyogenes strain NCTC10876]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1138480 DQM47_RS07525 WP_002985680.1 1457475..1458476(-) (ccpA) [Streptococcus pyogenes strain NCTC10876]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTATC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGTGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559