Detailed information NTG1138445

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQM47_RS00685
• Genome accession: NZ_LS483360
• Coordinates: 104945..105379 (+)
• Length: 144 a.a.
• NCBI ID: WP_002992738.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10876
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99945..110379

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM47_RS00655 (NCTC10876_00131)	-	101614..101979 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQM47_RS00660 (NCTC10876_00132)	comYA	102072..103010 (+)	939	WP_023079010.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM47_RS00665 (NCTC10876_00133)	comYB	102946..103980 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM47_RS00670 (NCTC10876_00134)	comYC	103982..104308 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM47_RS00675 (NCTC10876_00135)	comGD	104283..104711 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQM47_RS00680 (NCTC10876_00136)	comGE	104668..104952 (+)	285	WP_032465969.1	competence type IV pilus minor pilin ComGE	-
DQM47_RS00685 (NCTC10876_00137)	comYF	104945..105379 (+)	435	WP_002992738.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM47_RS00690 (NCTC10876_00138)	comGG	105363..105689 (+)	327	WP_085577408.1	competence type IV pilus minor pilin ComGG	-
DQM47_RS00695 (NCTC10876_00139)	comYH	105787..106740 (+)	954	WP_023610878.1	class I SAM-dependent methyltransferase	Machinery gene
DQM47_RS00700 (NCTC10876_00140)	-	106799..107995 (+)	1197	WP_010921803.1	acetate kinase	-
DQM47_RS00705	-	108182..108490 (+)	309	Protein_89	hypothetical protein	-
DQM47_RS00710 (NCTC10876_00141)	proC	108573..109343 (-)	771	WP_023610882.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16645.27 Da
• Isoelectric Point: 10.2526

>NTDB_id=1138445 DQM47_RS00685 WP_002992738.1 104945..105379(+) (comYF) [Streptococcus pyogenes strain NCTC10876]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1138445 DQM47_RS00685 WP_002992738.1 104945..105379(+) (comYF) [Streptococcus pyogenes strain NCTC10876]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCTTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396