Detailed information NTG1138381

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: DQM70_RS09515
• Genome accession: NZ_LS483358
• Coordinates: 2011142..2011798 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain NCTC11384
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2006142..2016798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM70_RS09495 (NCTC11384_01923)	nanA	2006515..2007393 (+)	879	WP_005605800.1	N-acetylneuraminate lyase	-
DQM70_RS09500 (NCTC11384_01924)	nagB	2007443..2008246 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
DQM70_RS09505 (NCTC11384_01925)	nagA	2008298..2009443 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
DQM70_RS09510 (NCTC11384_01926)	fumC	2009593..2010987 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
DQM70_RS09515 (NCTC11384_01927)	sxy/tfoX	2011142..2011798 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
DQM70_RS09520 (NCTC11384_01928)	rpsJ	2012206..2012517 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
DQM70_RS09525 (NCTC11384_01929)	rplC	2012543..2013169 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
DQM70_RS09530 (NCTC11384_01930)	rplD	2013185..2013787 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
DQM70_RS09535 (NCTC11384_01931)	rplW	2013784..2014089 (+)	306	WP_005605807.1	50S ribosomal protein L23	-
DQM70_RS09540 (NCTC11384_01932)	rplB	2014110..2014931 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
DQM70_RS09545 (NCTC11384_01933)	rpsS	2014959..2015234 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
DQM70_RS09550 (NCTC11384_01934)	rplV	2015245..2015577 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
DQM70_RS09555 (NCTC11384_01935)	rpsC	2015596..2016303 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
DQM70_RS09560 (NCTC11384_01936)	rplP	2016317..2016727 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1138381 DQM70_RS09515 WP_005609196.1 2011142..2011798(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain NCTC11384]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1138381 DQM70_RS09515 WP_005609196.1 2011142..2011798(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain NCTC11384]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376