Detailed information NTG1138268

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM51_RS02545
• Genome accession: NZ_LS483356
• Coordinates: 452374..453375 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8230
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 447374..458375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM51_RS02520 (NCTC8230_00499)	-	448048..448731 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
DQM51_RS02525 (NCTC8230_00500)	-	448942..449868 (-)	927	WP_002985688.1	glycosyltransferase family 2 protein	-
DQM51_RS02530 (NCTC8230_00501)	-	450013..450390 (-)	378	WP_002985686.1	VOC family protein	-
DQM51_RS02535 (NCTC8230_00502)	-	450401..451066 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM51_RS02540 (NCTC8230_00503)	-	451115..452200 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQM51_RS02545 (NCTC8230_00504)	ccpA	452374..453375 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM51_RS02550 (NCTC8230_00505)	-	453506..454504 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM51_RS02555 (NCTC8230_00506)	-	454506..455840 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
DQM51_RS02560 (NCTC8230_00508)	thrS	456262..458205 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1138268 DQM51_RS02545 WP_002985680.1 452374..453375(+) (ccpA) [Streptococcus pyogenes strain NCTC8230]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1138268 DQM51_RS02545 WP_002985680.1 452374..453375(+) (ccpA) [Streptococcus pyogenes strain NCTC8230]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGAGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559