Detailed information NTG1137985

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM42_RS02495
• Genome accession: NZ_LS483351
• Coordinates: 442252..443253 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8195
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 437252..448253

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM42_RS02470 (NCTC8195_00495)	-	437926..438609 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
DQM42_RS02475 (NCTC8195_00496)	-	438820..439746 (-)	927	WP_002985688.1	glycosyltransferase family 2 protein	-
DQM42_RS02480 (NCTC8195_00497)	-	439891..440268 (-)	378	WP_002985686.1	VOC family protein	-
DQM42_RS02485 (NCTC8195_00498)	-	440279..440944 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM42_RS02490 (NCTC8195_00499)	-	440993..442078 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQM42_RS02495 (NCTC8195_00500)	ccpA	442252..443253 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM42_RS02500 (NCTC8195_00501)	-	443384..444382 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM42_RS02505 (NCTC8195_00502)	-	444384..445718 (+)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
DQM42_RS02510 (NCTC8195_00504)	thrS	446140..448083 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1137985 DQM42_RS02495 WP_002985680.1 442252..443253(+) (ccpA) [Streptococcus pyogenes strain NCTC8195]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1137985 DQM42_RS02495 WP_002985680.1 442252..443253(+) (ccpA) [Streptococcus pyogenes strain NCTC8195]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGAGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559