Detailed information NTG1137780

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM50_RS07735
• Genome accession: NZ_LS483347
• Coordinates: 1482260..1483261 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8324
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1477260..1488261

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM50_RS07720 (NCTC8324_01554)	thrS	1477430..1479373 (-)	1944	WP_085613884.1	threonine--tRNA ligase	-
DQM50_RS07725 (NCTC8324_01556)	-	1479795..1481129 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DQM50_RS07730 (NCTC8324_01557)	-	1481131..1482129 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM50_RS07735 (NCTC8324_01558)	ccpA	1482260..1483261 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM50_RS07740 (NCTC8324_01559)	-	1483435..1484520 (+)	1086	WP_085613885.1	aminopeptidase P family protein	-
DQM50_RS07745 (NCTC8324_01560)	-	1484569..1485234 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM50_RS07750 (NCTC8324_01561)	-	1485245..1485622 (+)	378	WP_002985686.1	VOC family protein	-
DQM50_RS07755 (NCTC8324_01562)	-	1485767..1486693 (+)	927	WP_002985688.1	glycosyltransferase family 2 protein	-
DQM50_RS07760 (NCTC8324_01563)	-	1486904..1487587 (+)	684	WP_030126098.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1137780 DQM50_RS07735 WP_002985680.1 1482260..1483261(-) (ccpA) [Streptococcus pyogenes strain NCTC8324]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1137780 DQM50_RS07735 WP_002985680.1 1482260..1483261(-) (ccpA) [Streptococcus pyogenes strain NCTC8324]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGCGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559