Detailed information NTG1137661

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL69_RS06870
• Genome accession: NZ_LS483345
• Coordinates: 1364819..1365820 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8231
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1359819..1370820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL69_RS06855 (NCTC8231_01360)	thrS	1359990..1361933 (-)	1944	WP_111690798.1	threonine--tRNA ligase	-
DQL69_RS06860 (NCTC8231_01362)	-	1362355..1363689 (-)	1335	WP_047235925.1	glycosyltransferase family 4 protein	-
DQL69_RS06865 (NCTC8231_01363)	-	1363691..1364689 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQL69_RS06870 (NCTC8231_01364)	ccpA	1364819..1365820 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL69_RS06875 (NCTC8231_01365)	-	1365994..1367079 (+)	1086	WP_047235926.1	aminopeptidase P family protein	-
DQL69_RS06880 (NCTC8231_01366)	-	1367128..1367793 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL69_RS06885 (NCTC8231_01367)	-	1367804..1368181 (+)	378	WP_047235927.1	VOC family protein	-
DQL69_RS06890 (NCTC8231_01368)	-	1368326..1369252 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DQL69_RS06895 (NCTC8231_01369)	-	1369461..1370144 (+)	684	WP_012560521.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1137661 DQL69_RS06870 WP_002985680.1 1364819..1365820(-) (ccpA) [Streptococcus pyogenes strain NCTC8231]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1137661 DQL69_RS06870 WP_002985680.1 1364819..1365820(-) (ccpA) [Streptococcus pyogenes strain NCTC8231]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCCGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559