Detailed information NTG1137319

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM35_RS06880
• Genome accession: NZ_LS483338
• Coordinates: 1343691..1344692 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC12064
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1338691..1349692

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM35_RS06865 (NCTC12064_01360)	thrS	1338861..1340804 (-)	1944	WP_012560525.1	threonine--tRNA ligase	-
DQM35_RS06870 (NCTC12064_01362)	-	1341226..1342560 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
DQM35_RS06875 (NCTC12064_01363)	-	1342562..1343560 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM35_RS06880 (NCTC12064_01364)	ccpA	1343691..1344692 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM35_RS06885 (NCTC12064_01365)	-	1344866..1345951 (+)	1086	WP_012560524.1	aminopeptidase P family protein	-
DQM35_RS06890 (NCTC12064_01366)	-	1346000..1346665 (+)	666	WP_012560523.1	NAD(P)H-dependent oxidoreductase	-
DQM35_RS06895 (NCTC12064_01367)	-	1346676..1347053 (+)	378	WP_111679860.1	VOC family protein	-
DQM35_RS06900 (NCTC12064_01368)	-	1347198..1348124 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DQM35_RS06905 (NCTC12064_01369)	-	1348335..1349018 (+)	684	WP_038431232.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1137319 DQM35_RS06880 WP_002985680.1 1343691..1344692(-) (ccpA) [Streptococcus pyogenes strain NCTC12064]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1137319 DQM35_RS06880 WP_002985680.1 1343691..1344692(-) (ccpA) [Streptococcus pyogenes strain NCTC12064]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTTGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCAGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559