Detailed information NTG1137187

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL08_RS02300
• Genome accession: NZ_LS483336
• Coordinates: 420805..421806 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC12046
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 415805..426806

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL08_RS02275 (NCTC12046_00448)	-	416479..417162 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
DQL08_RS02280 (NCTC12046_00449)	-	417373..418299 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
DQL08_RS02285 (NCTC12046_00450)	-	418444..418821 (-)	378	WP_002985686.1	VOC family protein	-
DQL08_RS02290 (NCTC12046_00451)	-	418832..419497 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL08_RS02295 (NCTC12046_00452)	-	419546..420631 (-)	1086	WP_011054264.1	aminopeptidase P family protein	-
DQL08_RS02300 (NCTC12046_00453)	ccpA	420805..421806 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL08_RS02305 (NCTC12046_00454)	-	421937..422935 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQL08_RS02310 (NCTC12046_00455)	-	422937..424271 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
DQL08_RS02315 (NCTC12046_00457)	thrS	424693..426636 (+)	1944	WP_023611556.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1137187 DQL08_RS02300 WP_002985680.1 420805..421806(+) (ccpA) [Streptococcus pyogenes strain NCTC12046]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1137187 DQL08_RS02300 WP_002985680.1 420805..421806(+) (ccpA) [Streptococcus pyogenes strain NCTC12046]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559