Detailed information NTG1137172

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQL08_RS00690
• Genome accession: NZ_LS483336
• Coordinates: 104795..105229 (+)
• Length: 144 a.a.
• NCBI ID: WP_002992738.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12046
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99795..110229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL08_RS00660 (NCTC12046_00132)	-	101464..101829 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQL08_RS00665 (NCTC12046_00133)	comYA	101922..102860 (+)	939	WP_023611500.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL08_RS00670 (NCTC12046_00134)	comYB	102796..103830 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL08_RS00675 (NCTC12046_00135)	comYC	103832..104158 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL08_RS00680 (NCTC12046_00136)	comGD	104133..104561 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQL08_RS00685 (NCTC12046_00137)	comGE	104518..104802 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
DQL08_RS00690 (NCTC12046_00138)	comYF	104795..105229 (+)	435	WP_002992738.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL08_RS00695 (NCTC12046_00139)	comGG	105213..105539 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
DQL08_RS00700 (NCTC12046_00140)	comYH	105637..106590 (+)	954	WP_023611497.1	class I SAM-dependent methyltransferase	Machinery gene
DQL08_RS00705 (NCTC12046_00141)	-	106649..107845 (+)	1197	WP_111687938.1	acetate kinase	-
DQL08_RS00710	-	108032..108340 (+)	309	WP_010921804.1	hypothetical protein	-
DQL08_RS00715 (NCTC12046_00142)	proC	108423..109193 (-)	771	WP_023611530.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16645.27 Da
• Isoelectric Point: 10.2526

>NTDB_id=1137172 DQL08_RS00690 WP_002992738.1 104795..105229(+) (comYF) [Streptococcus pyogenes strain NCTC12046]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1137172 DQL08_RS00690 WP_002992738.1 104795..105229(+) (comYF) [Streptococcus pyogenes strain NCTC12046]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396