Detailed information NTG1137129

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL44_RS02260
• Genome accession: NZ_LS483335
• Coordinates: 411064..412065 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8332
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 406064..417065

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL44_RS02235 (NCTC8332_00435)	-	406738..407421 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
DQL44_RS02240 (NCTC8332_00436)	-	407632..408558 (-)	927	WP_111677098.1	glycosyltransferase family 2 protein	-
DQL44_RS02245 (NCTC8332_00437)	-	408703..409080 (-)	378	WP_002985686.1	VOC family protein	-
DQL44_RS02250 (NCTC8332_00438)	-	409091..409756 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL44_RS02255 (NCTC8332_00439)	-	409805..410890 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQL44_RS02260 (NCTC8332_00440)	ccpA	411064..412065 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL44_RS02265 (NCTC8332_00441)	-	412196..413194 (+)	999	WP_111677099.1	glycosyltransferase family 4 protein	-
DQL44_RS02270 (NCTC8332_00442)	-	413196..414530 (+)	1335	WP_111677100.1	glycosyltransferase family 4 protein	-
DQL44_RS02275 (NCTC8332_00444)	thrS	414952..416895 (+)	1944	WP_111677101.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1137129 DQL44_RS02260 WP_002985680.1 411064..412065(+) (ccpA) [Streptococcus pyogenes strain NCTC8332]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1137129 DQL44_RS02260 WP_002985680.1 411064..412065(+) (ccpA) [Streptococcus pyogenes strain NCTC8332]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559