Detailed information NTG1137091

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: DQL28_RS07030
• Genome accession: NZ_LS483334
• Coordinates: 1392619..1393971 (-)
• Length: 450 a.a.
• NCBI ID: WP_111676637.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12050
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1387619..1398971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL28_RS07020 (NCTC12050_01397)	rnc	1390671..1391363 (-)	693	WP_002990670.1	ribonuclease III	-
DQL28_RS07025 (NCTC12050_01398)	vicX	1391806..1392615 (-)	810	WP_002985641.1	MBL fold metallo-hydrolase	Regulator
DQL28_RS07030 (NCTC12050_01399)	vicK	1392619..1393971 (-)	1353	WP_111676637.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQL28_RS07035 (NCTC12050_01400)	vicR	1393964..1394674 (-)	711	WP_002985645.1	response regulator YycF	Regulator
DQL28_RS07040 (NCTC12050_01401)	-	1394836..1395870 (-)	1035	WP_011284595.1	DUF3114 domain-containing protein	-
DQL28_RS07045 (NCTC12050_01402)	-	1395926..1397173 (-)	1248	WP_002995606.1	AMP-binding protein	-
DQL28_RS07050 (NCTC12050_01403)	-	1397130..1398278 (-)	1149	WP_111676640.1	acetyl-CoA C-acyltransferase	-
DQL28_RS07055 (NCTC12050_01404)	-	1398247..1398816 (-)	570	WP_111676642.1	hypothetical protein	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51433.90 Da
• Isoelectric Point: 5.4026

>NTDB_id=1137091 DQL28_RS07030 WP_111676637.1 1392619..1393971(-) (vicK) [Streptococcus pyogenes strain NCTC12050]
MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTVTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD

Nucleotide

• Length: 1353 bp

>NTDB_id=1137091 DQL28_RS07030 WP_111676637.1 1392619..1393971(-) (vicK) [Streptococcus pyogenes strain NCTC12050]
ATGACTAGAGATATCATTGGAAACTTATCCACATTTGAATTAGCGATCCTTATCTTACTTGTTTTTGTTGCTTTTTACTT
TATCCATCTTGCGGTGCGTGACTACCGAAATGCACGTATTATTCGGATGATGAGCCATAAAATTCGAGACTTGATTAATG
GTCGCTATACTGATATAATCGACGAAAAAGCAGACATTGAGTTAATGGAGCTTTCAGACCAGTTAAATGACCTGTCAGAT
GTTTTTCGCTTGACGCATGAAAATCTTGCCCAAGAAAAAAATCGCTTGGCAAGTATTTTGGCTTATATGTCAGATGGTGT
ACTTGCTACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAATTAAATTTAAGTAAAGAAGAGG
CACTAAAGAAAAACATTACAGATTTGTTAGAAGGTGATACTTCATATACCTACCGTGATTTGGTATCCAAAACACCAGTG
GTAACTGTTAATAGCCGAAATGATATGGGTGAGTTTGTCTCATTACGCTTGCGTTTTGCGTTGAATAGGAGAGAGAGTGG
TTTTATTTCGGGCTTGGTTGTGGTGCTCCATGACACCACAGAACAAGAAAAAGAAGAACGTGAACGCCGTCTTTTTGTCT
CTAATGTAAGTCATGAATTAAGGACCCCTTTAACTTCGGTTAAATCCTACTTGGAGGCTCTTGATGAAGGTGCACTTAAA
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCAGATCTTTTAAA
CCTGTCTCGGATTGATAATCAAGTAACCCAATTAGCAGTAGAGATGACTAATTTTACTGCTTTTATAACTTCTATTTTAA
ACAGATTTGATTTGGTTAAAAATCAGCATACAGTTACAGGAAAAGTCTATGAAATTGTAAGAGATTACCCTATTACCTCT
GTCTGGCTTGAAATTGATAATGATAAAATGACACAGGTTATCGAGAATATTTTGAACAATGCCATTAAGTATTCTCCAGA
TGGTGGAAAAATTACAGTCCGTATGAAAACAACAGATACCCAATTAATTATTTCCATTTCAGACCAAGGACTAGGTATCC
CTAAAACAGATTTGCCTCTTATTTTTGATCGGTTCTATCGTGTAGACAAGGCAAGAAGTCGTGCCCAAGGAGGGACCGGT
CTAGGCCTTGCCATTGCTAAAGAAATCATCAAGCAGCACCATGGCTTTATCTGGGCTAAGAGTGACTATGGTAAAGGATC
GACCTTTACTATTGTCTTGCCTTATGAAAAAGATGCAGCCATCTATGAAGAATGGGAGGAAGATGTAGACTAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-162)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	72.705	92	0.669
micB	Streptococcus pneumoniae Cp1015	67.765	94.444	0.64