Detailed information NTG1136811

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL27_RS05970
• Genome accession: NZ_LS483329
• Coordinates: 1168976..1169977 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC12058
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1163976..1174977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL27_RS05955 (NCTC12058_01190)	thrS	1164146..1166089 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
DQL27_RS05960 (NCTC12058_01192)	-	1166511..1167845 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DQL27_RS05965 (NCTC12058_01193)	-	1167847..1168845 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQL27_RS05970 (NCTC12058_01194)	ccpA	1168976..1169977 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL27_RS05975 (NCTC12058_01195)	-	1170151..1171236 (+)	1086	WP_031488434.1	aminopeptidase P family protein	-
DQL27_RS05980 (NCTC12058_01196)	-	1171285..1171950 (+)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
DQL27_RS05985 (NCTC12058_01197)	-	1171961..1172338 (+)	378	WP_002985686.1	VOC family protein	-
DQL27_RS05990 (NCTC12058_01198)	-	1172483..1173409 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
DQL27_RS05995 (NCTC12058_01199)	-	1173620..1174303 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1136811 DQL27_RS05970 WP_002985680.1 1168976..1169977(-) (ccpA) [Streptococcus pyogenes strain NCTC12058]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1136811 DQL27_RS05970 WP_002985680.1 1168976..1169977(-) (ccpA) [Streptococcus pyogenes strain NCTC12058]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559