Detailed information NTG1136782

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQL27_RS00800
• Genome accession: NZ_LS483329
• Coordinates: 118208..118642 (+)
• Length: 144 a.a.
• NCBI ID: WP_111711329.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12058
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 113208..123642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL27_RS00770 (NCTC12058_00155)	-	114877..115242 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQL27_RS00775 (NCTC12058_00156)	comYA	115335..116273 (+)	939	WP_023612548.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL27_RS00780 (NCTC12058_00157)	comYB	116209..117243 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL27_RS00785 (NCTC12058_00158)	comYC	117245..117571 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL27_RS00790 (NCTC12058_00159)	comGD	117546..117974 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQL27_RS00795 (NCTC12058_00160)	comGE	117931..118215 (+)	285	WP_011284422.1	competence type IV pilus minor pilin ComGE	-
DQL27_RS00800 (NCTC12058_00161)	comYF	118208..118642 (+)	435	WP_111711329.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL27_RS00805 (NCTC12058_00162)	comGG	118626..118952 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
DQL27_RS00810 (NCTC12058_00163)	comYH	119050..120003 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
DQL27_RS00815 (NCTC12058_00164)	-	120062..121258 (+)	1197	WP_111711330.1	acetate kinase	-
DQL27_RS00820	-	121445..121753 (+)	309	WP_011284425.1	hypothetical protein	-
DQL27_RS00825 (NCTC12058_00165)	proC	121836..122606 (-)	771	WP_011284426.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16626.22 Da
• Isoelectric Point: 10.1406

>NTDB_id=1136782 DQL27_RS00800 WP_111711329.1 118208..118642(+) (comYF) [Streptococcus pyogenes strain NCTC12058]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLAHHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1136782 DQL27_RS00800 WP_111711329.1 118208..118642(+) (comYF) [Streptococcus pyogenes strain NCTC12058]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCATCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (42-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396