Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQL47_RS07365 Genome accession   NZ_LS483328
Coordinates   1534542..1535894 (-) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC12090     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1529542..1540894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL47_RS07345 (NCTC12090_01486) rnc 1530384..1531076 (-) 693 WP_111690571.1 ribonuclease III -
  DQL47_RS07350 (NCTC12090_01487) - 1531335..1532849 (-) 1515 WP_021320991.1 helix-turn-helix domain-containing protein -
  DQL47_RS07360 (NCTC12090_01488) vicX 1533729..1534538 (-) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  DQL47_RS07365 (NCTC12090_01489) vicK 1534542..1535894 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL47_RS07370 (NCTC12090_01490) vicR 1535887..1536597 (-) 711 WP_012515994.1 response regulator YycF Regulator
  DQL47_RS07375 (NCTC12090_01491) - 1536806..1537822 (-) 1017 WP_111690572.1 DUF3114 domain-containing protein -
  DQL47_RS07380 (NCTC12090_01492) - 1537868..1539130 (-) 1263 WP_111690290.1 AMP-binding protein -
  DQL47_RS07385 (NCTC12090_01493) - 1539120..1540235 (-) 1116 WP_111690291.1 acetyl-CoA C-acyltransferase -
  DQL47_RS07390 (NCTC12090_01494) - 1540232..1540771 (-) 540 WP_043053282.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=1136750 DQL47_RS07365 WP_014623188.1 1534542..1535894(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1136750 DQL47_RS07365 WP_014623188.1 1534542..1535894(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCATAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAACGACCTATCAGAT
GTTTTTCGTCTGACCCATGAAAACCTTGCCCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCGCTGCGGCTGCGTTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATTACCTCT
ATTTGGCTAGAAATTGACAATGACAAAATGACGCAGGTTATCGAAAATATTTTAAACAATGCAATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGGACCGGC
TTAGGGCTGGCTATTGCTAAAGAAATTATCAAGCAGCATCGAGGCTTTATTTGGGCCAAGAGCGATTATGGCAAGGGCTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment