Detailed information NTG1136744

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQL47_RS05225
• Genome accession: NZ_LS483328
• Coordinates: 1083945..1084682 (+)
• Length: 245 a.a.
• NCBI ID: WP_111690110.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC12090
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1078945..1089682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL47_RS05195 (NCTC12090_01044)	-	1079396..1080301 (-)	906	WP_111690108.1	diacylglycerol/lipid kinase family protein	-
DQL47_RS05200 (NCTC12090_01045)	trhA	1080411..1081061 (-)	651	WP_042670617.1	PAQR family membrane homeostasis protein TrhA	-
DQL47_RS05205 (NCTC12090_01046)	-	1081045..1081500 (-)	456	WP_012515587.1	DUF1836 domain-containing protein	-
DQL47_RS05210 (NCTC12090_01047)	-	1081760..1082515 (+)	756	WP_111690109.1	class I SAM-dependent methyltransferase	-
DQL47_RS05215 (NCTC12090_01048)	-	1082543..1082881 (+)	339	WP_043040548.1	cupin domain-containing protein	-
DQL47_RS05220 (NCTC12090_01049)	-	1082883..1083188 (+)	306	WP_043040549.1	AraC family ligand binding domain-containing protein	-
DQL47_RS05225 (NCTC12090_01050)	comE/blpR	1083945..1084682 (+)	738	WP_111690110.1	response regulator transcription factor	Regulator
DQL47_RS05230	-	1085055..1085260 (+)	206	Protein_997	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQL47_RS05235 (NCTC12090_01052)	-	1085327..1086181 (+)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
DQL47_RS05240 (NCTC12090_01053)	-	1086187..1087350 (+)	1164	WP_043030788.1	ABC transporter permease subunit	-
DQL47_RS05245 (NCTC12090_01054)	-	1087612..1087842 (+)	231	WP_012515596.1	Blp family class II bacteriocin	-
DQL47_RS05255 (NCTC12090_01056)	-	1088712..1088993 (+)	282	WP_080332480.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28928.29 Da
• Isoelectric Point: 7.9840

>NTDB_id=1136744 DQL47_RS05225 WP_111690110.1 1083945..1084682(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTYDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=1136744 DQL47_RS05225 WP_111690110.1 1083945..1084682(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAGCAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTATGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACCACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACCCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTACGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (18-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.868	98.776	0.453
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367