Detailed information NTG1136611

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL59_RS01375
• Genome accession: NZ_LS483326
• Coordinates: 231770..232771 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC12045
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 226770..237771

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL59_RS01350 (NCTC12045_00263)	-	227443..228126 (-)	684	WP_111681010.1	DUF969 domain-containing protein	-
DQL59_RS01355 (NCTC12045_00264)	-	228337..229263 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
DQL59_RS01360 (NCTC12045_00265)	-	229408..229785 (-)	378	WP_002985686.1	VOC family protein	-
DQL59_RS01365 (NCTC12045_00266)	-	229796..230461 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL59_RS01370 (NCTC12045_00267)	-	230510..231595 (-)	1086	WP_111681011.1	aminopeptidase P family protein	-
DQL59_RS01375 (NCTC12045_00268)	ccpA	231770..232771 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL59_RS01380 (NCTC12045_00269)	-	232902..233900 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQL59_RS01385 (NCTC12045_00270)	-	233902..235236 (+)	1335	WP_111681012.1	glycosyltransferase family 4 protein	-
DQL59_RS01390 (NCTC12045_00272)	thrS	235658..237601 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1136611 DQL59_RS01375 WP_002985680.1 231770..232771(+) (ccpA) [Streptococcus pyogenes strain NCTC12045]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1136611 DQL59_RS01375 WP_002985680.1 231770..232771(+) (ccpA) [Streptococcus pyogenes strain NCTC12045]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCTAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559