Detailed information NTG1136489

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL15_RS06780
• Genome accession: NZ_LS483323
• Coordinates: 1345016..1346017 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8300
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1340016..1351017

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL15_RS06765 (NCTC8300_01341)	thrS	1340186..1342129 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
DQL15_RS06770 (NCTC8300_01343)	-	1342551..1343885 (-)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
DQL15_RS06775 (NCTC8300_01344)	-	1343887..1344885 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DQL15_RS06780 (NCTC8300_01345)	ccpA	1345016..1346017 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL15_RS06785 (NCTC8300_01346)	-	1346191..1347276 (+)	1086	WP_002990707.1	aminopeptidase P family protein	-
DQL15_RS06790 (NCTC8300_01347)	-	1347325..1347990 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL15_RS06795 (NCTC8300_01348)	-	1348001..1348378 (+)	378	WP_002985686.1	VOC family protein	-
DQL15_RS06800 (NCTC8300_01349)	-	1348523..1349449 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
DQL15_RS06805 (NCTC8300_01350)	-	1349660..1350343 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1136489 DQL15_RS06780 WP_002985680.1 1345016..1346017(-) (ccpA) [Streptococcus pyogenes strain NCTC8300]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1136489 DQL15_RS06780 WP_002985680.1 1345016..1346017(-) (ccpA) [Streptococcus pyogenes strain NCTC8300]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559