Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   DQL06_RS09755 Genome accession   NZ_LS483321
Coordinates   1455051..1455254 (-) Length   67 a.a.
NCBI ID   WP_331792677.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8314     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1450051..1460254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL06_RS07495 (NCTC8314_01503) - 1450450..1450650 (-) 201 WP_002985729.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DQL06_RS07500 (NCTC8314_01504) - 1450663..1450890 (-) 228 WP_002992018.1 Blp family class II bacteriocin -
  DQL06_RS07505 (NCTC8314_01505) comA/nlmT 1451174..1453327 (+) 2154 WP_111689643.1 peptide cleavage/export ABC transporter Regulator
  DQL06_RS07510 - 1453338..1454701 (+) 1364 Protein_1406 bacteriocin secretion accessory protein -
  DQL06_RS07515 (NCTC8314_01508) - 1454778..1454903 (+) 126 WP_011017462.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQL06_RS09755 comD/blpH 1455051..1455254 (-) 204 WP_331792677.1 GHKL domain-containing protein Regulator
  DQL06_RS09760 (NCTC8314_01509) - 1455271..1456008 (-) 738 WP_231870884.1 hypothetical protein -
  DQL06_RS07525 (NCTC8314_01510) comE/blpR 1456387..1457136 (-) 750 WP_030126108.1 response regulator transcription factor Regulator
  DQL06_RS07530 (NCTC8314_01511) - 1457371..1458864 (-) 1494 WP_111689644.1 IS1182 family transposase -
  DQL06_RS09765 - 1459073..1460163 (-) 1091 Protein_1412 IS3 family transposase -

Sequence

Protein


Download         Length: 67 a.a.        Molecular weight: 7609.77 Da        Isoelectric Point: 7.0084

>NTDB_id=1136392 DQL06_RS09755 WP_331792677.1 1455051..1455254(-) (comD/blpH) [Streptococcus pyogenes strain NCTC8314]
MLIVQNDTFEKQINLSTIFERGVSSKGNNRGVGLSNVREILESYPTVTLKTVSNHFVFKQILEIEIL

Nucleotide


Download         Length: 204 bp        

>NTDB_id=1136392 DQL06_RS09755 WP_331792677.1 1455051..1455254(-) (comD/blpH) [Streptococcus pyogenes strain NCTC8314]
ATATTAATTGTTCAAAATGATACTTTTGAAAAACAGATTAATCTTTCCACGATTTTTGAGCGAGGTGTTTCTTCAAAAGG
AAATAATAGGGGAGTTGGTTTATCAAATGTTAGGGAGATATTAGAATCATATCCCACTGTTACCCTCAAAACAGTAAGTA
ATCATTTTGTTTTTAAACAGATTCTAGAAATAGAAATCCTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

50.769

97.015

0.493
  comD/comD2 Streptococcus gordonii strain NCTC7865

44.068

88.06

0.388
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

44.068

88.06

0.388

Multiple sequence alignment