Detailed information NTG1136377

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL06_RS07365
• Genome accession: NZ_LS483321
• Coordinates: 1428968..1429969 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8314
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1423968..1434969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL06_RS07350 (NCTC8314_01477)	thrS	1424138..1426081 (-)	1944	WP_111689632.1	threonine--tRNA ligase	-
DQL06_RS07355 (NCTC8314_01479)	-	1426503..1427837 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DQL06_RS07360 (NCTC8314_01480)	-	1427839..1428837 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQL06_RS07365 (NCTC8314_01481)	ccpA	1428968..1429969 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL06_RS07370 (NCTC8314_01482)	-	1430143..1431228 (+)	1086	WP_111689633.1	aminopeptidase P family protein	-
DQL06_RS07375 (NCTC8314_01483)	-	1431277..1431942 (+)	666	WP_111689634.1	NAD(P)H-dependent oxidoreductase	-
DQL06_RS07380 (NCTC8314_01484)	-	1431953..1432330 (+)	378	WP_002985686.1	VOC family protein	-
DQL06_RS07385 (NCTC8314_01485)	-	1432475..1433401 (+)	927	WP_111689635.1	glycosyltransferase family 2 protein	-
DQL06_RS07390 (NCTC8314_01486)	-	1433612..1434295 (+)	684	WP_111689636.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1136377 DQL06_RS07365 WP_002985680.1 1428968..1429969(-) (ccpA) [Streptococcus pyogenes strain NCTC8314]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1136377 DQL06_RS07365 WP_002985680.1 1428968..1429969(-) (ccpA) [Streptococcus pyogenes strain NCTC8314]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGTGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCTAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559