Detailed information NTG1136284

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQL31_RS00690
• Genome accession: NZ_LS483320
• Coordinates: 105912..106346 (+)
• Length: 144 a.a.
• NCBI ID: WP_002986542.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC5164
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 100912..111346

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL31_RS00660 (NCTC5164_00133)	-	102581..102946 (+)	366	WP_111676997.1	DUF1033 family protein	-
DQL31_RS00665 (NCTC5164_00134)	comYA	103039..103977 (+)	939	WP_063812149.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL31_RS00670 (NCTC5164_00135)	comYB	103913..104947 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL31_RS00675 (NCTC5164_00136)	comYC	104949..105275 (+)	327	WP_111676998.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL31_RS00680 (NCTC5164_00137)	comGD	105250..105678 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQL31_RS00685 (NCTC5164_00138)	comGE	105635..105919 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
DQL31_RS00690 (NCTC5164_00139)	comYF	105912..106346 (+)	435	WP_002986542.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL31_RS00695 (NCTC5164_00140)	comGG	106330..106656 (+)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
DQL31_RS00700 (NCTC5164_00141)	comYH	106754..107707 (+)	954	WP_111676999.1	class I SAM-dependent methyltransferase	Machinery gene
DQL31_RS00705 (NCTC5164_00142)	-	107766..108962 (+)	1197	WP_020904834.1	acetate kinase	-
DQL31_RS00710	-	109149..109457 (+)	309	WP_111677000.1	hypothetical protein	-
DQL31_RS00715 (NCTC5164_00143)	proC	109540..110310 (-)	771	WP_111677001.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16573.20 Da
• Isoelectric Point: 10.3584

>NTDB_id=1136284 DQL31_RS00690 WP_002986542.1 105912..106346(+) (comYF) [Streptococcus pyogenes strain NCTC5164]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1136284 DQL31_RS00690 WP_002986542.1 105912..106346(+) (comYF) [Streptococcus pyogenes strain NCTC5164]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396