Detailed information NTG1136077

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL11_RS07050
• Genome accession: NZ_LS483315
• Coordinates: 1387457..1388458 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC12059
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1382457..1393458

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL11_RS07035 (NCTC12059_01406)	thrS	1382627..1384570 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
DQL11_RS07040 (NCTC12059_01408)	-	1384992..1386326 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
DQL11_RS07045 (NCTC12059_01409)	-	1386328..1387326 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQL11_RS07050 (NCTC12059_01410)	ccpA	1387457..1388458 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL11_RS07055 (NCTC12059_01411)	-	1388632..1389717 (+)	1086	WP_085634187.1	aminopeptidase P family protein	-
DQL11_RS07060 (NCTC12059_01412)	-	1389766..1390431 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL11_RS07065 (NCTC12059_01413)	-	1390442..1390819 (+)	378	WP_002985686.1	VOC family protein	-
DQL11_RS07070 (NCTC12059_01414)	-	1390964..1391890 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
DQL11_RS07075 (NCTC12059_01415)	-	1392101..1392784 (+)	684	WP_030126098.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1136077 DQL11_RS07050 WP_002985680.1 1387457..1388458(-) (ccpA) [Streptococcus pyogenes strain NCTC12059]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1136077 DQL11_RS07050 WP_002985680.1 1387457..1388458(-) (ccpA) [Streptococcus pyogenes strain NCTC12059]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559