Detailed information NTG1135484

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM39_RS07770
• Genome accession: NZ_LS483298
• Coordinates: 1486151..1487152 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8225
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1481151..1492152

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM39_RS07755 (NCTC8225_01559)	thrS	1481321..1483264 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
DQM39_RS07760 (NCTC8225_01561)	-	1483686..1485020 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
DQM39_RS07765 (NCTC8225_01562)	-	1485022..1486020 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM39_RS07770 (NCTC8225_01563)	ccpA	1486151..1487152 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM39_RS07775 (NCTC8225_01564)	-	1487326..1488411 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQM39_RS07780 (NCTC8225_01565)	-	1488460..1489125 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM39_RS07785 (NCTC8225_01566)	-	1489136..1489513 (+)	378	WP_002985686.1	VOC family protein	-
DQM39_RS07790 (NCTC8225_01567)	-	1489658..1490584 (+)	927	WP_002985688.1	glycosyltransferase family 2 protein	-
DQM39_RS07795 (NCTC8225_01568)	-	1490795..1491478 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1135484 DQM39_RS07770 WP_002985680.1 1486151..1487152(-) (ccpA) [Streptococcus pyogenes strain NCTC8225]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1135484 DQM39_RS07770 WP_002985680.1 1486151..1487152(-) (ccpA) [Streptococcus pyogenes strain NCTC8225]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGAGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559