Detailed information NTG1132117

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H1W86_RS03145
• Genome accession: NZ_LR822042
• Coordinates: 592100..593101 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_1358
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 587100..598101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W86_RS03125 (STHERMO_0650)	smpB	588207..588671 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
H1W86_RS03130 (STHERMO_0651)	-	588825..590231 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
H1W86_RS03135 (STHERMO_0652)	-	590233..590598 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H1W86_RS03140 (STHERMO_0653)	-	590701..591786 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
H1W86_RS03145 (STHERMO_0654)	ccpA	592100..593101 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
H1W86_RS03150 (STHERMO_0655)	-	593160..593357 (+)	198	WP_014608125.1	hypothetical protein	-
H1W86_RS09620 (STHERMO_0656)	-	593463..593687 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
H1W86_RS03155 (STHERMO_0657)	-	593688..594227 (+)	540	WP_232086715.1	MmcQ/YjbR family DNA-binding protein	-
H1W86_RS03160 (STHERMO_0658)	-	594240..595355 (+)	1116	WP_180479721.1	glycerate kinase	-
H1W86_RS03165 (STHERMO_0659)	-	595402..595857 (-)	456	WP_011680938.1	YueI family protein	-
H1W86_RS03170 (STHERMO_0660)	eno	596066..597370 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
H1W86_RS03175 (STHERMO_0661)	-	597522..597707 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1132117 H1W86_RS03145 WP_004197422.1 592100..593101(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1358]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1132117 H1W86_RS03145 WP_004197422.1 592100..593101(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1358]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547