Detailed information NTG1132085

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H1W94_RS08665
• Genome accession: NZ_LR822041
• Coordinates: 1667561..1667998 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1122
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1662561..1672998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W94_RS08630 (STHERMO_1922)	-	1662615..1663277 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
H1W94_RS08635 (STHERMO_1924)	-	1663380..1663828 (-)	449	Protein_1638	CAAX protease	-
H1W94_RS09980 (STHERMO_1925)	-	1663902..1664327 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
H1W94_RS08645 (STHERMO_1927)	-	1664570..1664767 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
H1W94_RS08650 (STHERMO_1928)	-	1665016..1666209 (-)	1194	WP_022096898.1	acetate kinase	-
H1W94_RS08655 (STHERMO_1929)	comYH	1666265..1667221 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H1W94_RS08660 (STHERMO_1930)	comGG	1667266..1667583 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
H1W94_RS08665 (STHERMO_1931)	comYF	1667561..1667998 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
H1W94_RS08670 (STHERMO_1932)	comGE	1667982..1668275 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H1W94_RS08675 (STHERMO_1933)	comYD	1668247..1668675 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H1W94_RS08680 (STHERMO_1934)	comYC	1668635..1668961 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H1W94_RS08685 (STHERMO_1935)	comYB	1668958..1670058 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
H1W94_RS08690 (STHERMO_1936)	comGA/cglA/cilD	1669940..1670881 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
H1W94_RS08695 (STHERMO_1937)	-	1670962..1671324 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=1132085 H1W94_RS08665 WP_014608742.1 1667561..1667998(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1122]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1132085 H1W94_RS08665 WP_014608742.1 1667561..1667998(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441