Detailed information NTG1131995

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H1W80_RS03170
• Genome accession: NZ_LR822040
• Coordinates: 588033..589034 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_1125
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 583033..594034

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W80_RS03150 (STHERMO_0663)	smpB	584138..584602 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
H1W80_RS03155 (STHERMO_0664)	-	584756..586162 (+)	1407	WP_180473464.1	Cof-type HAD-IIB family hydrolase	-
H1W80_RS03160 (STHERMO_0665)	-	586164..586529 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H1W80_RS03165 (STHERMO_0666)	-	586632..587717 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
H1W80_RS03170 (STHERMO_0667)	ccpA	588033..589034 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
H1W80_RS03175 (STHERMO_0668)	-	589093..589290 (+)	198	WP_011225705.1	hypothetical protein	-
H1W80_RS03180 (STHERMO_0669)	-	589396..590160 (+)	765	WP_087009786.1	MmcQ/YjbR family DNA-binding protein	-
H1W80_RS03185 (STHERMO_0670)	-	590175..591290 (+)	1116	WP_002950249.1	glycerate kinase	-
H1W80_RS03190 (STHERMO_0671)	-	591329..591784 (-)	456	WP_087009787.1	YueI family protein	-
H1W80_RS03195 (STHERMO_0672)	eno	591992..593296 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
H1W80_RS03200	-	593450..593634 (-)	185	Protein_566	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1131995 H1W80_RS03170 WP_004197422.1 588033..589034(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1125]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1131995 H1W80_RS03170 WP_004197422.1 588033..589034(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1125]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCGAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547