Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H1X13_RS05495 Genome accession   NZ_LR822034
Coordinates   1052519..1053859 (-) Length   446 a.a.
NCBI ID   WP_011227273.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1049     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1047519..1058859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X13_RS05465 (STHERMO_1218) - 1047639..1048025 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  H1X13_RS05470 - 1048117..1048995 (-) 879 Protein_1037 GNAT family N-acetyltransferase -
  H1X13_RS05475 (STHERMO_1222) yidA 1049203..1050012 (+) 810 WP_011226081.1 sugar-phosphatase -
  H1X13_RS05480 (STHERMO_1223) - 1050014..1051228 (+) 1215 WP_011227270.1 aminoacyltransferase -
  H1X13_RS05485 (STHERMO_1224) - 1051280..1051641 (-) 362 Protein_1040 YbaN family protein -
  H1X13_RS05490 (STHERMO_1225) vicX 1051701..1052513 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  H1X13_RS05495 (STHERMO_1226) vicK 1052519..1053859 (-) 1341 WP_011227273.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H1X13_RS05500 (STHERMO_1227) vicR 1053852..1054559 (-) 708 WP_011226084.1 response regulator YycF Regulator
  H1X13_RS05505 (STHERMO_1228) - 1055083..1055850 (+) 768 WP_179966655.1 amino acid ABC transporter ATP-binding protein -
  H1X13_RS05510 (STHERMO_1229) - 1055862..1056695 (+) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  H1X13_RS05515 (STHERMO_1230) - 1056713..1057411 (+) 699 WP_011226087.1 amino acid ABC transporter permease -
  H1X13_RS05520 (STHERMO_1231) - 1057423..1058073 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50768.12 Da        Isoelectric Point: 5.2464

>NTDB_id=1131707 H1X13_RS05495 WP_011227273.1 1052519..1053859(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_1049]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1131707 H1X13_RS05495 WP_011227273.1 1052519..1053859(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_1049]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGGTCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(37-79)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment