Detailed information NTG1131577

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H1W91_RS03260
• Genome accession: NZ_LR822032
• Coordinates: 609977..610978 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_1050
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 604977..615978

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W91_RS03240 (STHERMO_0683)	smpB	606079..606543 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
H1W91_RS03245 (STHERMO_0684)	-	606697..608103 (+)	1407	WP_002950242.1	Cof-type HAD-IIB family hydrolase	-
H1W91_RS03250 (STHERMO_0685)	-	608105..608470 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H1W91_RS03255 (STHERMO_0686)	-	608573..609658 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
H1W91_RS03260 (STHERMO_0687)	ccpA	609977..610978 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
H1W91_RS03265 (STHERMO_0688)	-	611037..611234 (+)	198	WP_180476878.1	MmcQ family protein	-
H1W91_RS03270 (STHERMO_0689)	-	611340..612104 (+)	765	WP_180476879.1	MmcQ/YjbR family DNA-binding protein	-
H1W91_RS03275 (STHERMO_0690)	-	612119..613234 (+)	1116	WP_011227015.1	glycerate kinase	-
H1W91_RS03280 (STHERMO_0691)	-	613280..613735 (-)	456	WP_002950250.1	YueI family protein	-
H1W91_RS03285 (STHERMO_0692)	eno	613944..615248 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
H1W91_RS03290	-	615401..615585 (-)	185	Protein_587	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1131577 H1W91_RS03260 WP_004197422.1 609977..610978(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1050]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1131577 H1W91_RS03260 WP_004197422.1 609977..610978(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCGAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547