Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   H1W74_RS06520 Genome accession   NZ_LR822031
Coordinates   1268317..1270284 (-) Length   655 a.a.
NCBI ID   WP_096811568.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   internalize XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1248283..1314730 1268317..1270284 within 0


Gene organization within MGE regions


Location: 1248283..1314730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS06425 (STHERMO_1463) liaF 1248291..1248989 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H1W74_RS09815 (STHERMO_1464) - 1249244..1249411 (-) 168 WP_232089277.1 ion channel -
  H1W74_RS06435 (STHERMO_1467) stkP/pknB 1250048..1251919 (-) 1872 WP_002946880.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H1W74_RS06440 (STHERMO_1468) - 1251919..1252656 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  H1W74_RS06445 (STHERMO_1469) rsmB 1252700..1254022 (-) 1323 WP_014608533.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  H1W74_RS06450 (STHERMO_1470) fmt 1254012..1254947 (-) 936 WP_002946883.1 methionyl-tRNA formyltransferase -
  H1W74_RS06455 (STHERMO_1471) - 1254965..1257361 (-) 2397 WP_176243306.1 primosomal protein N' -
  H1W74_RS06460 (STHERMO_1472) rpoZ 1257503..1257817 (-) 315 WP_002951415.1 DNA-directed RNA polymerase subunit omega -
  H1W74_RS06465 (STHERMO_1473) gmk 1257839..1258468 (-) 630 WP_022096878.1 guanylate kinase -
  H1W74_RS06470 (STHERMO_1474) ftsY 1258701..1260092 (-) 1392 WP_011681410.1 signal recognition particle-docking protein FtsY -
  H1W74_RS06475 (STHERMO_1475) - 1260103..1260921 (-) 819 WP_011681411.1 Cof-type HAD-IIB family hydrolase -
  H1W74_RS06480 (STHERMO_1476) - 1260914..1261708 (-) 795 WP_022096877.1 HAD-IIB family hydrolase -
  H1W74_RS06485 (STHERMO_1478) - 1261892..1262269 (+) 378 WP_011226300.1 GntR family transcriptional regulator -
  H1W74_RS06490 (STHERMO_1479) - 1262274..1262972 (+) 699 WP_022096876.1 ABC transporter ATP-binding protein -
  H1W74_RS06495 (STHERMO_1480) - 1262984..1263769 (+) 786 WP_002951425.1 hypothetical protein -
  H1W74_RS06500 (STHERMO_1481) amiF 1263819..1264748 (-) 930 WP_002946407.1 ATP-binding cassette domain-containing protein Regulator
  H1W74_RS06505 (STHERMO_1482) amiE 1264741..1265826 (-) 1086 WP_002946408.1 ABC transporter ATP-binding protein Regulator
  H1W74_RS06510 (STHERMO_1483) amiD 1265836..1266762 (-) 927 WP_002946409.1 oligopeptide ABC transporter permease OppC Regulator
  H1W74_RS06515 (STHERMO_1484) amiC 1266762..1268255 (-) 1494 WP_002946410.1 ABC transporter permease Regulator
  H1W74_RS06520 (STHERMO_1485) amiA 1268317..1270284 (-) 1968 WP_096811568.1 peptide ABC transporter substrate-binding protein Regulator
  H1W74_RS06525 - 1270488..1270678 (-) 191 Protein_1246 IS3 family transposase -
  H1W74_RS10205 - 1270672..1271082 (-) 411 Protein_1247 ATP-binding cassette domain-containing protein -
  H1W74_RS06540 - 1271114..1271428 (-) 315 Protein_1248 TatD family hydrolase -
  H1W74_RS06545 (STHERMO_1489) - 1271777..1272982 (+) 1206 WP_011227415.1 OFA family MFS transporter -
  H1W74_RS06550 - 1273029..1274381 (-) 1353 Protein_1250 IS3 family transposase -
  H1W74_RS06555 (STHERMO_1495) pta 1274467..1275450 (-) 984 WP_022097032.1 phosphate acetyltransferase -
  H1W74_RS06560 (STHERMO_1496) - 1275464..1276360 (-) 897 WP_011226316.1 RluA family pseudouridine synthase -
  H1W74_RS06565 (STHERMO_1497) - 1276357..1277193 (-) 837 WP_022097031.1 NAD kinase -
  H1W74_RS06570 (STHERMO_1498) - 1277165..1277839 (-) 675 WP_002951443.1 GTP pyrophosphokinase family protein -
  H1W74_RS06575 (STHERMO_1499) - 1277935..1278510 (+) 576 WP_002951444.1 CYTH domain-containing protein -
  H1W74_RS06580 (STHERMO_1500) - 1278873..1279844 (+) 972 WP_002951446.1 ribose-phosphate diphosphokinase -
  H1W74_RS06585 (STHERMO_1501) - 1279848..1280960 (+) 1113 WP_002948029.1 cysteine desulfurase family protein -
  H1W74_RS06590 (STHERMO_1502) - 1280962..1281309 (+) 348 WP_002948028.1 DUF1831 domain-containing protein -
  H1W74_RS06595 (STHERMO_1503) - 1281453..1282112 (+) 660 WP_002948027.1 redox-sensing transcriptional repressor Rex -
  H1W74_RS06600 (STHERMO_1504) - 1282105..1282800 (+) 696 WP_002948026.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  H1W74_RS06605 (STHERMO_1505) radC 1282853..1283539 (-) 687 WP_002948025.1 RadC family protein -
  H1W74_RS06610 (STHERMO_1506) - 1283588..1285372 (-) 1785 WP_002948024.1 rhamnan synthesis F family protein -
  H1W74_RS06615 (STHERMO_1507) - 1285369..1286424 (-) 1056 WP_002948022.1 glycosyltransferase family 2 protein -
  H1W74_RS06620 (STHERMO_1508) - 1286444..1287649 (-) 1206 WP_014727633.1 ABC transporter ATP-binding protein -
  H1W74_RS06625 (STHERMO_1509) - 1287649..1288458 (-) 810 WP_002948020.1 ABC transporter permease -
  H1W74_RS06630 (STHERMO_1510) - 1288442..1289398 (-) 957 WP_014727634.1 glycosyltransferase family 2 protein -
  H1W74_RS06635 (STHERMO_1511) cps2T 1289395..1290543 (-) 1149 WP_002948014.1 beta 1-4 rhamnosyltransferase Cps2T -
  H1W74_RS06640 (STHERMO_1512) - 1290652..1291662 (-) 1011 WP_022097029.1 glycosyltransferase family 2 protein -
  H1W74_RS06645 (STHERMO_1513) - 1291662..1292936 (-) 1275 WP_022097028.1 lipopolysaccharide biosynthesis protein -
  H1W74_RS06650 (STHERMO_1514) - 1292929..1293261 (-) 333 WP_011226332.1 DUF2304 domain-containing protein -
  H1W74_RS06655 (STHERMO_1515) - 1293267..1293962 (-) 696 WP_173940715.1 glycosyltransferase family 2 protein -
  H1W74_RS06660 (STHERMO_1516) rfbD 1294039..1294890 (-) 852 WP_022097027.1 dTDP-4-dehydrorhamnose reductase -
  H1W74_RS06665 (STHERMO_1517) - 1294967..1296301 (-) 1335 WP_002946422.1 DUF6056 family protein -
  H1W74_RS06670 (STHERMO_1518) - 1296414..1297331 (-) 918 WP_002946425.1 glycosyltransferase family 2 protein -
  H1W74_RS06675 (STHERMO_1519) - 1297394..1298809 (-) 1416 WP_022097026.1 DUF2142 domain-containing protein -
  H1W74_RS06680 (STHERMO_1521) - 1299143..1299478 (-) 336 WP_002891474.1 metal-sulfur cluster assembly factor -
  H1W74_RS06685 (STHERMO_1522) rpoD 1299532..1300641 (-) 1110 WP_011226338.1 RNA polymerase sigma factor RpoD -
  H1W74_RS06690 (STHERMO_1523) dnaG 1300645..1302456 (-) 1812 WP_011681448.1 DNA primase -
  H1W74_RS06695 (STHERMO_1524) mscL 1302597..1302680 (+) 84 Protein_1279 large conductance mechanosensitive channel protein MscL -
  H1W74_RS06700 (STHERMO_1525) rpsU 1302840..1303016 (-) 177 WP_082309068.1 30S ribosomal protein S21 -
  H1W74_RS06705 (STHERMO_1526) - 1303211..1304005 (-) 795 WP_022097025.1 ABC transporter substrate-binding protein -
  H1W74_RS06710 (STHERMO_1527) - 1304067..1305176 (-) 1110 WP_022097024.1 aminotransferase -
  H1W74_RS06715 (STHERMO_1528) - 1305522..1306319 (-) 798 WP_022097023.1 transporter substrate-binding domain-containing protein -
  H1W74_RS06720 (STHERMO_1529) - 1306316..1307146 (-) 831 WP_022097022.1 transporter substrate-binding domain-containing protein -
  H1W74_RS06725 (STHERMO_1530) - 1307360..1307824 (-) 465 WP_011681454.1 8-oxo-dGTP diphosphatase -
  H1W74_RS06730 (STHERMO_1531) uvrB 1307869..1309860 (-) 1992 WP_002953358.1 excinuclease ABC subunit UvrB -
  H1W74_RS06735 (STHERMO_1532) - 1310007..1310474 (-) 468 WP_022097021.1 hypothetical protein -
  H1W74_RS10115 - 1310547..1311483 (-) 937 Protein_1288 CPBP family intramembrane glutamic endopeptidase -
  H1W74_RS06745 (STHERMO_1536) - 1311682..1313892 (+) 2211 WP_173940613.1 ABC transporter substrate-binding protein/permease -
  H1W74_RS06750 (STHERMO_1537) - 1313892..1314632 (+) 741 WP_002945131.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 71600.64 Da        Isoelectric Point: 5.1811

>NTDB_id=1131535 H1W74_RS06520 WP_096811568.1 1268317..1270284(-) (amiA) [Streptococcus thermophilus isolate STH_CIRM_1047]
MKKSKWLALAGVALLGVGVLAACSSKSSTSGTTYSNIYGSDPETLDYITSIMGGTKAVLTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADAKSGALYLVQDSIAGLSDYLSGANKDFSNVGVK
AIDDYTLQYTLKKQEPYWNSKTTYGVLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELTKNENYWDKK
NVHFDSIKFSYSDGSDLESIERSFSDGALSIARVFPTSSNYASVEKKYKDNIFYTEPGASTSVIGVNIDRQSYKFSAKKT
DAEKTSTKKALLNKDFRQSINFAIDRTAYQSQVNGKDGAALALRNLFVPYDFVSAGDKTFGDLVTEKMSSYGDEWSGVNF
ADGQDGLYNAKKAKTEFAKAKEALQGEGVQFPVHLDLPVDQSSKLSVAQAQSLKQTIEKSLGSENVVIDINQMSSDDMQN
ATSNAANAAAEDWDISNGVGWGPDYQDPSTYLDILKTTSSENTKAFNGYDDPNNAAAAQVGLKDYDALLDSAASETTDIN
ARYDRYAQAQAWLEDSSLIIPLTVSNGAAPVISRLTPFTGASIQVGDKGSSYVKYVKSQEKVVTKKEYEQSREKWLKEKK
ASNEKAQKDLEKHVK

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=1131535 H1W74_RS06520 WP_096811568.1 1268317..1270284(-) (amiA) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGAAAAAAAGCAAATGGTTGGCCCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCTTCTAAGTC
AAGTACTAGTGGAACGACTTATAGTAATATTTATGGCTCAGATCCAGAAACCTTGGATTATATTACATCAATTATGGGAG
GGACAAAAGCTGTTTTGACTAATGGTGTAGATGGTCTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTGACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAGCATGCCGCTGATGCCAAATCTGGAGCCCTTT
ATTTGGTACAAGATTCTATTGCTGGATTGTCTGACTACCTTTCTGGTGCCAATAAAGATTTCTCAAATGTTGGCGTTAAA
GCAATCGACGATTACACTCTGCAATACACACTAAAAAAACAGGAACCATACTGGAACTCTAAGACAACCTATGGTGTGCT
CTTCCCAGTTAACGAAGACTTTCTTAAGAACAAAGGGAAAGATTTTGGTAAGTCAACAGACCCAACCTCTATCCTATATA
ACGGTCCTTTCCTTCTTAAATCTTTGACAGCTAAATCATCTATCGAGTTGACTAAGAATGAGAATTATTGGGATAAGAAA
AACGTGCATTTTGACTCTATCAAATTCTCATATTCTGATGGATCGGATCTAGAATCAATAGAACGTAGTTTCTCTGACGG
CGCTCTCAGCATTGCACGTGTCTTCCCTACGAGTTCAAACTATGCATCGGTAGAAAAAAAATATAAAGATAATATTTTTT
ACACAGAACCAGGTGCATCTACATCGGTTATTGGTGTAAACATTGACCGCCAAAGCTATAAATTCTCAGCTAAGAAGACA
GATGCTGAAAAGACATCAACTAAGAAGGCTCTTCTAAACAAAGACTTTCGTCAATCAATCAACTTCGCTATTGATCGTAC
AGCCTATCAATCACAAGTAAACGGTAAAGATGGCGCAGCTCTTGCTCTACGTAACCTTTTTGTTCCTTATGATTTTGTCA
GTGCAGGTGATAAGACCTTTGGTGATCTTGTGACAGAAAAAATGAGCTCTTATGGTGATGAGTGGTCTGGTGTTAACTTT
GCAGATGGTCAAGACGGTCTCTACAATGCTAAAAAAGCTAAGACTGAGTTTGCCAAAGCCAAAGAGGCTCTTCAAGGAGA
AGGGGTACAATTCCCAGTTCACTTAGACCTTCCAGTTGATCAAAGTTCTAAACTTAGTGTTGCTCAAGCTCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAAATGTCATCTGATGATATGCAAAAT
GCGACTAGTAATGCGGCAAATGCTGCAGCAGAAGACTGGGATATTTCTAACGGTGTGGGTTGGGGTCCAGATTATCAAGA
TCCATCAACTTATCTTGATATCTTAAAAACAACATCAAGTGAAAATACCAAGGCTTTCAATGGTTATGATGATCCAAACA
ATGCAGCAGCAGCCCAAGTAGGTCTTAAGGATTATGATGCCTTGCTTGATTCAGCAGCTTCAGAAACAACAGACATCAAC
GCTCGTTACGACCGTTATGCTCAAGCCCAAGCTTGGTTGGAAGATAGCTCTCTTATCATTCCATTGACTGTTAGTAACGG
TGCAGCACCAGTTATCTCACGTTTGACACCATTTACGGGTGCTAGCATACAGGTGGGTGATAAGGGCTCATCCTACGTCA
AATATGTGAAATCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAAAAGAAA
GCATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(75-520)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

90.091

100

0.902
  amiA3 Streptococcus thermophilus LMD-9

88.128

100

0.884
  amiA3 Streptococcus thermophilus LMG 18311

87.823

100

0.881

Multiple sequence alignment