Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H1W74_RS05310 Genome accession   NZ_LR822031
Coordinates   1017448..1018788 (-) Length   446 a.a.
NCBI ID   WP_004197359.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1012448..1023788
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS05275 (STHERMO_1205) - 1012566..1012952 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  H1W74_RS09775 - 1013044..1013924 (-) 881 Protein_995 GNAT family N-acetyltransferase -
  H1W74_RS05290 (STHERMO_1208) yidA 1014132..1014941 (+) 810 WP_011226081.1 sugar-phosphatase -
  H1W74_RS05295 (STHERMO_1209) - 1014943..1016157 (+) 1215 WP_004197368.1 aminoacyltransferase -
  H1W74_RS05300 - 1016209..1016570 (-) 362 Protein_998 YbaN family protein -
  H1W74_RS05305 (STHERMO_1210) vicX 1016630..1017442 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  H1W74_RS05310 (STHERMO_1211) vicK 1017448..1018788 (-) 1341 WP_004197359.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H1W74_RS05315 (STHERMO_1212) vicR 1018781..1019488 (-) 708 WP_011226084.1 response regulator YycF Regulator
  H1W74_RS05320 (STHERMO_1214) - 1020015..1020782 (+) 768 WP_022096757.1 amino acid ABC transporter ATP-binding protein -
  H1W74_RS05325 (STHERMO_1215) - 1020794..1021627 (+) 834 WP_022096756.1 transporter substrate-binding domain-containing protein -
  H1W74_RS05330 (STHERMO_1216) - 1021645..1022343 (+) 699 WP_022096755.1 amino acid ABC transporter permease -
  H1W74_RS05335 (STHERMO_1217) - 1022355..1023005 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50780.18 Da        Isoelectric Point: 5.2464

>NTDB_id=1131525 H1W74_RS05310 WP_004197359.1 1017448..1018788(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_1047]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMINFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1131525 H1W74_RS05310 WP_004197359.1 1017448..1018788(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAACGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGATAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(37-79)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.155

92.825

0.688
  micB Streptococcus pneumoniae Cp1015

66.282

97.085

0.644

Multiple sequence alignment