Detailed information NTG1131520

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H1W74_RS03150
• Genome accession: NZ_LR822031
• Coordinates: 592319..593320 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_1047
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 587319..598320

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W74_RS03130 (STHERMO_0677)	smpB	588424..588888 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
H1W74_RS03135 (STHERMO_0678)	-	589042..590448 (+)	1407	WP_022096975.1	Cof-type HAD-IIB family hydrolase	-
H1W74_RS03140 (STHERMO_0679)	-	590450..590815 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H1W74_RS03145 (STHERMO_0680)	-	590918..592003 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
H1W74_RS03150 (STHERMO_0681)	ccpA	592319..593320 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
H1W74_RS03155 (STHERMO_0682)	-	593379..593576 (+)	198	WP_014608125.1	hypothetical protein	-
H1W74_RS03160 (STHERMO_0683)	-	593682..594446 (+)	765	WP_004197425.1	MmcQ/YjbR family DNA-binding protein	-
H1W74_RS03165 (STHERMO_0684)	-	594461..595576 (+)	1116	WP_022096976.1	glycerate kinase	-
H1W74_RS03170 (STHERMO_0685)	-	595615..596070 (-)	456	WP_022096977.1	YueI family protein	-
H1W74_RS03175 (STHERMO_0686)	eno	596279..597583 (+)	1305	WP_022096978.1	surface-displayed alpha-enolase	-
H1W74_RS03180	-	597736..597920 (-)	185	Protein_575	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1131520 H1W74_RS03150 WP_004197422.1 592319..593320(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1047]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1131520 H1W74_RS03150 WP_004197422.1 592319..593320(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCACCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGTCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547