Detailed information NTG1131412

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H1W89_RS06385
• Genome accession: NZ_LR822029
• Coordinates: 1218896..1219897 (-)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_1035
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1213896..1224897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W89_RS06355	-	1214291..1214475 (+)	185	Protein_1207	hypothetical protein	-
H1W89_RS06360 (STHERMO_1401)	eno	1214627..1215931 (-)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
H1W89_RS06365 (STHERMO_1402)	-	1216140..1216595 (+)	456	WP_011680938.1	YueI family protein	-
H1W89_RS06370 (STHERMO_1403)	-	1216642..1217757 (-)	1116	WP_011680937.1	glycerate kinase	-
H1W89_RS06375 (STHERMO_1404)	-	1217770..1218309 (-)	540	WP_232085838.1	MmcQ/YjbR family DNA-binding protein	-
H1W89_RS09925 (STHERMO_1405)	-	1218310..1218534 (-)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
H1W89_RS06380 (STHERMO_1406)	-	1218640..1218837 (-)	198	WP_014608125.1	hypothetical protein	-
H1W89_RS06385 (STHERMO_1407)	ccpA	1218896..1219897 (-)	1002	WP_004197422.1	catabolite control protein A	Regulator
H1W89_RS06390 (STHERMO_1408)	-	1220211..1221296 (+)	1086	WP_011680935.1	M24 family metallopeptidase	-
H1W89_RS06395 (STHERMO_1409)	-	1221399..1221764 (-)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H1W89_RS06400 (STHERMO_1410)	-	1221766..1223172 (-)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
H1W89_RS06405 (STHERMO_1411)	smpB	1223326..1223790 (-)	465	WP_002950240.1	SsrA-binding protein SmpB	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1131412 H1W89_RS06385 WP_004197422.1 1218896..1219897(-) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1035]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1131412 H1W89_RS06385 WP_004197422.1 1218896..1219897(-) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_1035]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547