Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H1X63_RS07690 Genome accession   NZ_LR822027
Coordinates   1487542..1488237 (-) Length   231 a.a.
NCBI ID   WP_180487733.1    Uniprot ID   A0A8D6UCZ2
Organism   Streptococcus thermophilus isolate STH_CIRM_998     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1482542..1493237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X63_RS07675 - 1483353..1483898 (-) 546 Protein_1450 GNAT family N-acetyltransferase -
  H1X63_RS07680 (STHERMO_1673) - 1483964..1485226 (-) 1263 WP_179972171.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H1X63_RS07685 (STHERMO_1674) - 1485312..1487552 (-) 2241 WP_179973926.1 DNA internalization-related competence protein ComEC/Rec2 -
  H1X63_RS07690 (STHERMO_1675) comEA 1487542..1488237 (-) 696 WP_180487733.1 helix-hairpin-helix domain-containing protein Machinery gene
  H1X63_RS07695 (STHERMO_1676) - 1488343..1489098 (-) 756 WP_179972174.1 lysophospholipid acyltransferase family protein -
  H1X63_RS11120 - 1489228..1490138 (+) 911 Protein_1455 polysaccharide deacetylase family protein -
  H1X63_RS07705 (STHERMO_1679) - 1490188..1490952 (+) 765 WP_179972175.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H1X63_RS07710 (STHERMO_1680) - 1490956..1491225 (+) 270 WP_179972176.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24577.63 Da        Isoelectric Point: 5.1113

>NTDB_id=1131359 H1X63_RS07690 WP_180487733.1 1487542..1488237(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_998]
MKEKILSYVNNNRLFVSIIGVLVVVFCFFLWMTCGAGNSMEAETSYTDVTTLSTSSSKQSSKSLTEVSSQSQTEGSEKVK
SKVTVDVKGAVVKPGVYTLKAGVRVTDVIQKAGGMTEDADAKSVNLAASLSDEEVIYVANKYENVSVLDQSGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTIPGIGAKRAEDIIAYHESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1131359 H1X63_RS07690 WP_180487733.1 1487542..1488237(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_998]
GTGAAGGAAAAGATTCTATCCTATGTTAACAATAATCGTCTATTTGTGAGTATAATTGGTGTTCTGGTGGTGGTTTTCTG
CTTCTTTCTGTGGATGACTTGTGGTGCCGGCAATAGCATGGAGGCAGAGACGTCTTATACAGATGTGACAACTTTGTCTA
CCTCTTCATCTAAACAAAGCTCAAAATCACTTACGGAAGTGTCTTCTCAGTCACAAACTGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAAGCCAGGTGTCTATACGCTAAAGGCAGGAGTTAGGGTGACAGA
TGTCATTCAGAAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAATATGAAAATGTTTCTGTCCTTGATCAATCAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTACAAACTATTCCTGGAATTGG
TGCCAAGAGGGCAGAGGATATTATCGCTTATCATGAAAGTCATGGTGGCTTTCAATCTGTGGATGATTTGAAAAATGTCT
CAGGGATCGGAGATAAGACTTTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

91.342

100

0.913
  comEA/celA/cilE Streptococcus mitis SK321

41.048

99.134

0.407
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.912

98.701

0.394

Multiple sequence alignment