Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H0511_RS07250 Genome accession   NZ_LR822017
Coordinates   1426952..1427647 (-) Length   231 a.a.
NCBI ID   WP_179973927.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1421952..1432647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS07235 - 1422763..1423308 (-) 546 Protein_1391 GNAT family N-acetyltransferase -
  H0511_RS07240 (STHERMO_1625) - 1423374..1424636 (-) 1263 WP_179972171.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H0511_RS07245 (STHERMO_1626) - 1424722..1426962 (-) 2241 WP_179973926.1 DNA internalization-related competence protein ComEC/Rec2 -
  H0511_RS07250 (STHERMO_1627) comEA 1426952..1427647 (-) 696 WP_179973927.1 helix-hairpin-helix domain-containing protein Machinery gene
  H0511_RS07255 (STHERMO_1628) - 1427753..1428508 (-) 756 WP_179973928.1 lysophospholipid acyltransferase family protein -
  H0511_RS10620 (STHERMO_1629) - 1428602..1428808 (+) 207 WP_232087319.1 hypothetical protein -
  H0511_RS10130 (STHERMO_1630) - 1428911..1429549 (+) 639 WP_269473445.1 polysaccharide deacetylase family protein -
  H0511_RS07265 (STHERMO_1631) - 1429599..1430363 (+) 765 WP_179972175.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H0511_RS07270 (STHERMO_1632) - 1430367..1430636 (+) 270 WP_179972176.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24596.68 Da        Isoelectric Point: 5.1200

>NTDB_id=1130981 H0511_RS07250 WP_179973927.1 1426952..1427647(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_336]
MKEKILSYVNNNRLFVSIIGVLVVVFCFFLWMTCGAGNSMEAETSYTDVTTLSTSSSKQSSKSLTEVSSQSQTEGSEKVK
SKVTVDVKGAVVKPGVYTLKAGVRVTDVIQKAGGMTEDADAKSVNLAASLSDEEVIYVANKYENVSVLDQSGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTIPGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESIYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1130981 H0511_RS07250 WP_179973927.1 1426952..1427647(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_336]
GTGAAGGAAAAGATTCTATCCTATGTTAACAATAATCGTCTATTTGTGAGTATAATTGGTGTTCTGGTGGTGGTTTTCTG
CTTCTTTCTGTGGATGACTTGTGGTGCCGGCAATAGCATGGAGGCAGAGACGTCTTATACAGATGTGACAACTTTGTCTA
CCTCTTCATCTAAACAAAGCTCAAAATCACTTACGGAAGTGTCTTCTCAGTCACAAACTGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAAGCCAGGTGTCTATACGCTAAAGGCAGGAGTTAGGGTGACAGA
TGTCATTCAGAAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAATATGAAAATGTTTCTGTCCTTGATCAATCAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTACAAACTATTCCTGGAATTGG
TGCCAAGAGGGCAGAGGATATTATCGCTTATCGTGAAAGTCATGGTGGCTTTCAATCTGTGGATGATTTGAAAAATGTCT
CAGGGATCGGAGATAAGACTTTAGATAAAATCAGAGAGTCCATCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

91.342

100

0.913
  comEA/celA/cilE Streptococcus mitis SK321

41.485

99.134

0.411
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

40.351

98.701

0.398
  comEA Latilactobacillus sakei subsp. sakei 23K

34.568

100

0.364

Multiple sequence alignment