Detailed information NTG1130697

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H0504_RS08520
• Genome accession: NZ_LR822011
• Coordinates: 1653980..1654417 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_23
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1648980..1659417

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0504_RS08485 (STHERMO_1903)	-	1649034..1649696 (-)	663	WP_179971686.1	CPBP family intramembrane glutamic endopeptidase	-
H0504_RS08490 (STHERMO_1905)	-	1649799..1650247 (-)	449	Protein_1635	CAAX protease	-
H0504_RS09850 (STHERMO_1906)	-	1650321..1650746 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
H0504_RS08500 (STHERMO_1908)	-	1650989..1651186 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
H0504_RS08505 (STHERMO_1909)	-	1651435..1652628 (-)	1194	WP_022096898.1	acetate kinase	-
H0504_RS08510 (STHERMO_1910)	comYH	1652684..1653640 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H0504_RS08515 (STHERMO_1911)	comGG	1653685..1654002 (-)	318	WP_011226623.1	competence type IV pilus minor pilin ComGG	-
H0504_RS08520 (STHERMO_1912)	comYF	1653980..1654417 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0504_RS08525 (STHERMO_1913)	comGE	1654401..1654694 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H0504_RS08530 (STHERMO_1914)	comYD	1654666..1655094 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H0504_RS08535 (STHERMO_1915)	comYC	1655054..1655380 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H0504_RS08540 (STHERMO_1916)	comYB	1655377..1656477 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0504_RS08545 (STHERMO_1917)	comGA/cglA/cilD	1656359..1657300 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
H0504_RS08550 (STHERMO_1918)	-	1657381..1657743 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=1130697 H0504_RS08520 WP_014608742.1 1653980..1654417(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_23]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1130697 H0504_RS08520 WP_014608742.1 1653980..1654417(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_23]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441