Detailed information NTG1130610

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H0507_RS03195
• Genome accession: NZ_LR822010
• Coordinates: 600451..601452 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_29
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 595451..606452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0507_RS03175 (STHERMO_0667)	smpB	596557..597021 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
H0507_RS03180 (STHERMO_0668)	-	597175..598581 (+)	1407	WP_179971857.1	Cof-type HAD-IIB family hydrolase	-
H0507_RS03185 (STHERMO_0669)	-	598583..598948 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H0507_RS03190 (STHERMO_0670)	-	599051..600136 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
H0507_RS03195 (STHERMO_0671)	ccpA	600451..601452 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
H0507_RS03200 (STHERMO_0672)	-	601511..601708 (+)	198	WP_011225705.1	hypothetical protein	-
H0507_RS03205 (STHERMO_0673)	-	601814..602578 (+)	765	WP_011225706.1	MmcQ/YjbR family DNA-binding protein	-
H0507_RS03210 (STHERMO_0674)	-	602593..603708 (+)	1116	WP_011227015.1	glycerate kinase	-
H0507_RS03215 (STHERMO_0675)	-	603747..604202 (-)	456	WP_002950250.1	YueI family protein	-
H0507_RS03220 (STHERMO_0676)	eno	604411..605715 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
H0507_RS03225	-	605867..606051 (-)	185	Protein_579	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1130610 H0507_RS03195 WP_004197422.1 600451..601452(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_29]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1130610 H0507_RS03195 WP_004197422.1 600451..601452(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_29]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547