Detailed information NTG1130552

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H0503_RS03180
• Genome accession: NZ_LR822009
• Coordinates: 602477..603478 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_19
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 597477..608478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0503_RS03160 (STHERMO_0683)	smpB	598583..599047 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
H0503_RS03165 (STHERMO_0684)	-	599201..600607 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
H0503_RS03170 (STHERMO_0685)	-	600609..600974 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H0503_RS03175 (STHERMO_0686)	-	601077..602162 (-)	1086	WP_011680935.1	M24 family metallopeptidase	-
H0503_RS03180 (STHERMO_0687)	ccpA	602477..603478 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
H0503_RS03185 (STHERMO_0688)	-	603537..603734 (+)	198	WP_014608125.1	hypothetical protein	-
H0503_RS09825 (STHERMO_0689)	-	603840..604064 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
H0503_RS03190 (STHERMO_0690)	-	604065..604604 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
H0503_RS03195 (STHERMO_0691)	-	604617..605732 (+)	1116	WP_011680937.1	glycerate kinase	-
H0503_RS03200 (STHERMO_0692)	-	605779..606234 (-)	456	WP_011680938.1	YueI family protein	-
H0503_RS03205 (STHERMO_0693)	eno	606443..607747 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
H0503_RS03210 (STHERMO_0694)	-	607899..608084 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1130552 H0503_RS03180 WP_004197422.1 602477..603478(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_19]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1130552 H0503_RS03180 WP_004197422.1 602477..603478(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547