Detailed information
Bioinformatically predicted
Overview
| Name | amiC | Type | Regulator |
| Locus tag | H0501_RS06850 | Genome accession | NZ_LR822008 |
| Coordinates | 1325897..1327390 (-) | Length | 497 a.a. |
| NCBI ID | WP_179970628.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus isolate STH_CIRM_18 | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1307425..1385156 | 1325897..1327390 | within | 0 |
Gene organization within MGE regions
Location: 1307425..1385156
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H0501_RS06760 (STHERMO_1496) | liaF | 1307433..1308131 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| H0501_RS10085 (STHERMO_1497) | - | 1308386..1308553 (-) | 168 | WP_014608530.1 | potassium channel family protein | - |
| H0501_RS06770 (STHERMO_1500) | stkP/pknB | 1309190..1311061 (-) | 1872 | WP_014621795.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| H0501_RS06775 (STHERMO_1501) | - | 1311061..1311798 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| H0501_RS06780 (STHERMO_1502) | rsmB | 1311842..1313164 (-) | 1323 | WP_179970630.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| H0501_RS06785 (STHERMO_1503) | fmt | 1313154..1314089 (-) | 936 | WP_014608534.1 | methionyl-tRNA formyltransferase | - |
| H0501_RS06790 (STHERMO_1504) | - | 1314107..1316503 (-) | 2397 | WP_014608535.1 | primosomal protein N' | - |
| H0501_RS06795 (STHERMO_1505) | rpoZ | 1316645..1316959 (-) | 315 | WP_179970629.1 | DNA-directed RNA polymerase subunit omega | - |
| H0501_RS06800 (STHERMO_1506) | gmk | 1316981..1317610 (-) | 630 | WP_014608537.1 | guanylate kinase | - |
| H0501_RS06805 (STHERMO_1507) | ftsY | 1317836..1319227 (-) | 1392 | WP_014608538.1 | signal recognition particle-docking protein FtsY | - |
| H0501_RS06810 (STHERMO_1508) | - | 1319241..1320056 (-) | 816 | WP_011226298.1 | Cof-type HAD-IIB family hydrolase | - |
| H0501_RS06815 (STHERMO_1509) | - | 1320049..1320843 (-) | 795 | WP_011681412.1 | HAD-IIB family hydrolase | - |
| H0501_RS06820 (STHERMO_1510) | - | 1321027..1321404 (+) | 378 | WP_011681413.1 | GntR family transcriptional regulator | - |
| H0501_RS06825 (STHERMO_1511) | - | 1321409..1322107 (+) | 699 | WP_014608540.1 | ABC transporter ATP-binding protein | - |
| H0501_RS06830 (STHERMO_1512) | - | 1322119..1322904 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| H0501_RS06835 (STHERMO_1513) | amiF | 1322954..1323883 (-) | 930 | WP_011681415.1 | ATP-binding cassette domain-containing protein | Regulator |
| H0501_RS06840 (STHERMO_1514) | amiE | 1323876..1324961 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| H0501_RS06845 (STHERMO_1515) | amiD | 1324971..1325897 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| H0501_RS06850 (STHERMO_1516) | amiC | 1325897..1327390 (-) | 1494 | WP_179970628.1 | ABC transporter permease | Regulator |
| H0501_RS06855 (STHERMO_1517) | amiA3 | 1327451..1329418 (-) | 1968 | WP_179970627.1 | peptide ABC transporter substrate-binding protein | Regulator |
| H0501_RS06860 (STHERMO_1519) | - | 1329724..1330871 (+) | 1148 | WP_095559415.1 | IS3 family transposase | - |
| H0501_RS06865 | - | 1330909..1331093 (-) | 185 | Protein_1314 | IS3 family transposase | - |
| H0501_RS10090 | - | 1331087..1331497 (-) | 411 | Protein_1315 | ATP-binding cassette domain-containing protein | - |
| H0501_RS06880 (STHERMO_1522) | - | 1331529..1331843 (-) | 315 | Protein_1316 | TatD family hydrolase | - |
| H0501_RS06885 (STHERMO_1523) | - | 1332192..1333397 (+) | 1206 | WP_011681420.1 | OFA family MFS transporter | - |
| H0501_RS06890 | - | 1333443..1334756 (-) | 1314 | Protein_1318 | IS3 family transposase | - |
| H0501_RS06895 (STHERMO_1528) | pta | 1334881..1335864 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| H0501_RS06900 (STHERMO_1529) | - | 1335878..1336774 (-) | 897 | WP_179970626.1 | RluA family pseudouridine synthase | - |
| H0501_RS06905 (STHERMO_1530) | - | 1336771..1337607 (-) | 837 | WP_041827075.1 | NAD kinase | - |
| H0501_RS06910 (STHERMO_1531) | - | 1337579..1338253 (-) | 675 | WP_002951443.1 | GTP pyrophosphokinase family protein | - |
| H0501_RS06915 (STHERMO_1532) | - | 1338349..1338924 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| H0501_RS06920 (STHERMO_1533) | - | 1339289..1340260 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| H0501_RS06925 (STHERMO_1534) | - | 1340264..1341376 (+) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| H0501_RS06930 (STHERMO_1535) | - | 1341378..1341725 (+) | 348 | WP_002948028.1 | DUF1831 domain-containing protein | - |
| H0501_RS06935 (STHERMO_1536) | - | 1341869..1342528 (+) | 660 | WP_011681430.1 | redox-sensing transcriptional repressor Rex | - |
| H0501_RS06940 (STHERMO_1537) | - | 1342521..1343216 (+) | 696 | WP_179970625.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| H0501_RS06945 (STHERMO_1538) | radC | 1343269..1343955 (-) | 687 | WP_011226324.1 | RadC family protein | - |
| H0501_RS06950 (STHERMO_1539) | - | 1344003..1345646 (-) | 1644 | WP_095559418.1 | rhamnan synthesis F family protein | - |
| H0501_RS06955 (STHERMO_1540) | - | 1345647..1346849 (-) | 1203 | WP_014608559.1 | ABC transporter ATP-binding protein | - |
| H0501_RS06960 (STHERMO_1541) | - | 1346849..1347655 (-) | 807 | WP_014608560.1 | ABC transporter permease | - |
| H0501_RS06965 (STHERMO_1542) | - | 1347656..1348594 (-) | 939 | WP_065972455.1 | glycosyltransferase family 2 protein | - |
| H0501_RS06970 (STHERMO_1543) | cps2T | 1348591..1349739 (-) | 1149 | WP_065972456.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| H0501_RS06975 (STHERMO_1545) | - | 1349939..1351456 (-) | 1518 | WP_179970624.1 | glucosyltransferase domain-containing protein | - |
| H0501_RS06980 (STHERMO_1546) | - | 1351473..1352720 (-) | 1248 | WP_101415660.1 | glycosyltransferase family 4 protein | - |
| H0501_RS06985 (STHERMO_1547) | - | 1352724..1354031 (-) | 1308 | WP_179970623.1 | DUF2142 domain-containing protein | - |
| H0501_RS06990 (STHERMO_1548) | - | 1354018..1357032 (-) | 3015 | WP_179970622.1 | rhamnan synthesis F family protein | - |
| H0501_RS06995 (STHERMO_1549) | - | 1357243..1358445 (-) | 1203 | WP_179970621.1 | hypothetical protein | - |
| H0501_RS07000 (STHERMO_1551) | - | 1358916..1359692 (-) | 777 | WP_179970620.1 | glycosyltransferase family 2 protein | - |
| H0501_RS07005 (STHERMO_1552) | - | 1359682..1360038 (-) | 357 | WP_011681441.1 | DUF2304 domain-containing protein | - |
| H0501_RS07010 (STHERMO_1553) | - | 1360038..1360754 (-) | 717 | WP_041827367.1 | glycosyltransferase family 2 protein | - |
| H0501_RS07015 (STHERMO_1554) | - | 1360784..1361776 (-) | 993 | WP_179970619.1 | glycosyltransferase family 8 protein | - |
| H0501_RS10580 | - | 1362605..1362700 (-) | 96 | WP_374110359.1 | glycosyltransferase | - |
| H0501_RS07020 (STHERMO_1556) | glf | 1362714..1363823 (-) | 1110 | WP_179970618.1 | UDP-galactopyranose mutase | - |
| H0501_RS07025 (STHERMO_1557) | - | 1363826..1365283 (-) | 1458 | WP_179970617.1 | flippase | - |
| H0501_RS07030 (STHERMO_1558) | - | 1365280..1366038 (-) | 759 | WP_179970616.1 | DUF4422 domain-containing protein | - |
| H0501_RS07035 (STHERMO_1559) | rfbD | 1366376..1367227 (-) | 852 | WP_100284792.1 | dTDP-4-dehydrorhamnose reductase | - |
| H0501_RS07040 (STHERMO_1560) | - | 1367300..1368559 (-) | 1260 | WP_232086458.1 | DUF2142 domain-containing protein | - |
| H0501_RS07045 (STHERMO_1561) | - | 1368614..1369540 (-) | 927 | WP_179970615.1 | glycosyltransferase family 2 protein | - |
| H0501_RS07050 (STHERMO_1562) | - | 1369551..1369886 (-) | 336 | WP_179970614.1 | metal-sulfur cluster assembly factor | - |
| H0501_RS07055 (STHERMO_1563) | rpoD | 1369940..1371049 (-) | 1110 | WP_179970613.1 | RNA polymerase sigma factor RpoD | - |
| H0501_RS07060 (STHERMO_1564) | dnaG | 1371053..1372864 (-) | 1812 | WP_116920323.1 | DNA primase | - |
| H0501_RS07065 (STHERMO_1565) | rpsU | 1373235..1373411 (-) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| H0501_RS07070 (STHERMO_1566) | - | 1373606..1374400 (-) | 795 | WP_014621826.1 | ABC transporter substrate-binding protein | - |
| H0501_RS07075 (STHERMO_1567) | - | 1374493..1375602 (-) | 1110 | WP_014727642.1 | aminotransferase | - |
| H0501_RS07080 (STHERMO_1568) | - | 1375949..1376746 (-) | 798 | WP_002951495.1 | transporter substrate-binding domain-containing protein | - |
| H0501_RS07085 (STHERMO_1569) | - | 1376743..1377573 (-) | 831 | WP_022097022.1 | transporter substrate-binding domain-containing protein | - |
| H0501_RS07090 (STHERMO_1570) | - | 1377787..1378251 (-) | 465 | WP_011681454.1 | 8-oxo-dGTP diphosphatase | - |
| H0501_RS07095 (STHERMO_1571) | uvrB | 1378296..1380287 (-) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| H0501_RS07100 | - | 1380399..1380650 (+) | 252 | WP_179970612.1 | hypothetical protein | - |
| H0501_RS07105 | - | 1380974..1381910 (-) | 937 | Protein_1362 | CPBP family intramembrane glutamic endopeptidase | - |
| H0501_RS07110 (STHERMO_1576) | - | 1382108..1384318 (+) | 2211 | WP_179970841.1 | ABC transporter substrate-binding protein/permease | - |
| H0501_RS07115 (STHERMO_1577) | - | 1384318..1385058 (+) | 741 | WP_011681459.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 497 a.a. Molecular weight: 55818.68 Da Isoelectric Point: 10.0158
>NTDB_id=1130509 H0501_RS06850 WP_179970628.1 1325897..1327390(-) (amiC) [Streptococcus thermophilus isolate STH_CIRM_18]
MKRYILLRTLRSILSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKINYENTIFERMGYIDYYDTKELQENAS
TLDKSVTTKPTKANKAIYQKYVDSLGHGWRLHQFKQSKQFYATRDVPVLERVFEFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNSQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTLFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
MKRYILLRTLRSILSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKINYENTIFERMGYIDYYDTKELQENAS
TLDKSVTTKPTKANKAIYQKYVDSLGHGWRLHQFKQSKQFYATRDVPVLERVFEFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNSQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTLFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
Nucleotide
Download Length: 1494 bp
>NTDB_id=1130509 H0501_RS06850 WP_179970628.1 1325897..1327390(-) (amiC) [Streptococcus thermophilus isolate STH_CIRM_18]
ATGAAAAGATATATTTTATTGAGAACCCTCCGTTCTATATTGTCAATATTTGTCGTGACGGCCTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAGGACCCGAACTACAATAAGATTGCAAAGACAGCTGATTCTAAGA
TAAACTATGAAAATACAATCTTTGAACGTATGGGGTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAATGCCAGC
ACACTTGATAAGTCGGTAACAACTAAGCCAACAAAAGCCAATAAAGCTATCTACCAAAAATATGTGGATAGTTTGGGACA
TGGCTGGCGTTTGCATCAGTTCAAGCAAAGTAAGCAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
AATTCTACACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTACATC
CGTATTGAAAATGATCCAGCTATTGGTTGGTCGGTTGTTGGTTCAGGGACTAAGCACAAATATTTGCTTTACTTTAACAG
TCAGTTCCCGTTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTATTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACACTCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGACTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
ATGAAAAGATATATTTTATTGAGAACCCTCCGTTCTATATTGTCAATATTTGTCGTGACGGCCTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAGGACCCGAACTACAATAAGATTGCAAAGACAGCTGATTCTAAGA
TAAACTATGAAAATACAATCTTTGAACGTATGGGGTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAATGCCAGC
ACACTTGATAAGTCGGTAACAACTAAGCCAACAAAAGCCAATAAAGCTATCTACCAAAAATATGTGGATAGTTTGGGACA
TGGCTGGCGTTTGCATCAGTTCAAGCAAAGTAAGCAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
AATTCTACACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTACATC
CGTATTGAAAATGATCCAGCTATTGGTTGGTCGGTTGTTGGTTCAGGGACTAAGCACAAATATTTGCTTTACTTTAACAG
TCAGTTCCCGTTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTATTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACACTCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGACTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiC | Streptococcus thermophilus LMG 18311 |
97.787 |
100 |
0.978 |
| amiC | Streptococcus thermophilus LMD-9 |
97.384 |
100 |
0.974 |
| amiC | Streptococcus salivarius strain HSISS4 |
96.378 |
100 |
0.964 |