Detailed information NTG1130494

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H0501_RS03315
• Genome accession: NZ_LR822008
• Coordinates: 632890..633891 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus isolate STH_CIRM_18
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 627890..638891

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0501_RS03295 (STHERMO_0696)	smpB	628997..629461 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
H0501_RS03300 (STHERMO_0697)	-	629615..631021 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
H0501_RS03305 (STHERMO_0698)	-	631023..631388 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
H0501_RS03310 (STHERMO_0699)	-	631491..632576 (-)	1086	WP_011680935.1	M24 family metallopeptidase	-
H0501_RS03315 (STHERMO_0700)	ccpA	632890..633891 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
H0501_RS03320 (STHERMO_0701)	-	633950..634147 (+)	198	WP_014608125.1	hypothetical protein	-
H0501_RS09900 (STHERMO_0702)	-	634253..634477 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
H0501_RS03325 (STHERMO_0703)	-	634478..635017 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
H0501_RS03330 (STHERMO_0704)	-	635030..636145 (+)	1116	WP_011680937.1	glycerate kinase	-
H0501_RS03335 (STHERMO_0705)	-	636192..636647 (-)	456	WP_011680938.1	YueI family protein	-
H0501_RS03340 (STHERMO_0706)	eno	636856..638160 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
H0501_RS03345 (STHERMO_0707)	-	638312..638497 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1130494 H0501_RS03315 WP_004197422.1 632890..633891(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_18]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1130494 H0501_RS03315 WP_004197422.1 632890..633891(+) (ccpA) [Streptococcus thermophilus isolate STH_CIRM_18]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547