Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   PERCYII40_RS24375 Genome accession   NZ_LR739071
Coordinates   5272814..5274151 (+) Length   445 a.a.
NCBI ID   WP_162288708.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain C7-25 isolate C7-25     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5267814..5279151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PERCYII40_RS24350 (PACF725_4867) pgeF 5267957..5268685 (-) 729 WP_003123393.1 peptidoglycan editing factor PgeF -
  PERCYII40_RS24355 (PACF725_4868) rluD 5268682..5269644 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  PERCYII40_RS24360 (PACF725_4869) - 5269790..5270815 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  PERCYII40_RS24365 (PACF725_4870) - 5270972..5271217 (+) 246 WP_009316269.1 PP0621 family protein -
  PERCYII40_RS24370 (PACF725_4871) pilS 5271207..5272799 (+) 1593 WP_003123394.1 two-component system sensor histidine kinase PilS Regulator
  PERCYII40_RS24375 (PACF725_4872) pilR 5272814..5274151 (+) 1338 WP_162288708.1 two-component system response regulator PilR Regulator
  PERCYII40_RS24380 (PACF725_4873) thiO 5274197..5275291 (-) 1095 WP_003123395.1 glycine oxidase ThiO -
  PERCYII40_RS24385 (PACF725_4874) - 5275426..5275935 (+) 510 WP_003102595.1 GspH/FimT family pseudopilin -
  PERCYII40_RS24390 (PACF725_4875) - 5276041..5276547 (+) 507 WP_003102598.1 GspH/FimT family pseudopilin -
  PERCYII40_RS24395 (PACF725_4876) pilV 5276538..5277095 (+) 558 WP_003119423.1 type 4a pilus minor pilin PilV Machinery gene
  PERCYII40_RS24400 (PACF725_4877) pilW 5277092..5277916 (+) 825 WP_003123396.1 type 4a pilus minor pilin PilW -
  PERCYII40_RS24405 (PACF725_4878) pilX 5277913..5278500 (+) 588 WP_003112826.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49721.02 Da        Isoelectric Point: 5.8654

>NTDB_id=1129728 PERCYII40_RS24375 WP_162288708.1 5272814..5274151(+) (pilR) [Pseudomonas aeruginosa strain C7-25 isolate C7-25]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPPRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=1129728 PERCYII40_RS24375 WP_162288708.1 5272814..5274151(+) (pilR) [Pseudomonas aeruginosa strain C7-25 isolate C7-25]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCCGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

50.98

100

0.526
  luxO Vibrio cholerae strain A1552

37.946

100

0.382

Multiple sequence alignment