Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GPW69_RS02100 Genome accession   NZ_LR738724
Coordinates   406097..407389 (+) Length   430 a.a.
NCBI ID   WP_074391009.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 401097..412389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS02075 - 401902..402543 (+) 642 WP_074391007.1 response regulator transcription factor -
  GPW69_RS02080 - 402593..403993 (+) 1401 WP_024377222.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GPW69_RS02085 - 403995..404366 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  GPW69_RS02090 cysK 404392..405318 (-) 927 WP_002937015.1 cysteine synthase A -
  GPW69_RS02095 - 405408..406040 (-) 633 WP_044769501.1 YigZ family protein -
  GPW69_RS02100 comFA/cflA 406097..407389 (+) 1293 WP_074391009.1 DEAD/DEAH box helicase Machinery gene
  GPW69_RS02105 - 407382..408047 (+) 666 WP_074391010.1 ComF family protein -
  GPW69_RS02110 hpf 408125..408667 (+) 543 WP_014637536.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48970.56 Da        Isoelectric Point: 9.1612

>NTDB_id=1129591 GPW69_RS02100 WP_074391009.1 406097..407389(+) (comFA/cflA) [Streptococcus suis isolate 9401240]
MKELENYYGRLFTKYQLAAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYVDNPMLYRAADNAVKETGVQVFLTATSTDEL
DKKVRTGKLNRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=1129591 GPW69_RS02100 WP_074391009.1 406097..407389(+) (comFA/cflA) [Streptococcus suis isolate 9401240]
ATGAAAGAACTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGGCAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTATTGTCGAGCCTGCCTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATTTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATCGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGTAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAACCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACGGGCAAATTAAACCGTCTTAGTTTGCCAAGGCGATTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGTTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATCGTTGAGGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTAACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCGGGCCGGGTCGGCAGGAGTATGGAACGTCCGACTGGG
TTACTCCAGTTTTATCATGAAGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGCTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

38.283

100

0.384
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363

Multiple sequence alignment