Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   GPW68_RS03650 Genome accession   NZ_LR738723
Coordinates   708019..709368 (+) Length   449 a.a.
NCBI ID   WP_024405653.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0088     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 703019..714368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS03625 - 704130..704789 (-) 660 WP_002935828.1 amino acid ABC transporter permease -
  GPW68_RS03630 - 704804..705502 (-) 699 WP_002935835.1 amino acid ABC transporter permease -
  GPW68_RS03635 - 705517..706356 (-) 840 WP_074389305.1 transporter substrate-binding domain-containing protein -
  GPW68_RS03640 - 706367..707128 (-) 762 WP_074389306.1 amino acid ABC transporter ATP-binding protein -
  GPW68_RS03645 micA 707322..708026 (+) 705 WP_002935840.1 response regulator YycF Regulator
  GPW68_RS03650 micB 708019..709368 (+) 1350 WP_024405653.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPW68_RS03655 vicX 709375..710178 (+) 804 WP_023369694.1 MBL fold metallo-hydrolase Regulator
  GPW68_RS03660 - 710518..710898 (+) 381 Protein_659 ATP-binding cassette domain-containing protein -
  GPW68_RS03665 pbp2b 710990..713065 (+) 2076 WP_024405652.1 penicillin-binding protein PBP2B -
  GPW68_RS03670 recR 713074..713670 (+) 597 WP_002935848.1 recombination mediator RecR -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51077.16 Da        Isoelectric Point: 4.4860

>NTDB_id=1129546 GPW68_RS03650 WP_024405653.1 708019..709368(+) (micB) [Streptococcus suis isolate GD-0088]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHINENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGYGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1129546 GPW68_RS03650 WP_024405653.1 708019..709368(+) (micB) [Streptococcus suis isolate GD-0088]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAGCAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGCTGGCTCAGACACCTGAG
ATTGTGATTGATCACATCAATGAAAATGAAGAATTTCTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTAGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTATTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTTATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment