Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GPW48_RS08000 Genome accession   NZ_LR738720
Coordinates   1570171..1571463 (-) Length   430 a.a.
NCBI ID   WP_074389963.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0001     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1565171..1576463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS07990 hpf 1568894..1569436 (-) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  GPW48_RS07995 - 1569513..1570178 (-) 666 WP_074389964.1 ComF family protein -
  GPW48_RS08000 comFA/cflA 1570171..1571463 (-) 1293 WP_074389963.1 DEAD/DEAH box helicase Machinery gene
  GPW48_RS08005 - 1571520..1572152 (+) 633 WP_171840851.1 YigZ family protein -
  GPW48_RS08010 cysK 1572242..1573168 (+) 927 WP_074389961.1 cysteine synthase A -
  GPW48_RS08015 - 1573194..1573565 (-) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  GPW48_RS08020 - 1573567..1574967 (-) 1401 WP_074389960.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GPW48_RS08025 - 1575017..1575658 (-) 642 WP_024394813.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48967.54 Da        Isoelectric Point: 9.0315

>NTDB_id=1129407 GPW48_RS08000 WP_074389963.1 1570171..1571463(-) (comFA/cflA) [Streptococcus suis isolate GD-0001]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDELVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
IFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQVAGRVGRSIERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=1129407 GPW48_RS08000 WP_074389963.1 1570171..1571463(-) (comFA/cflA) [Streptococcus suis isolate GD-0001]
ATGAAAGAATTAGAAAATTATTACGGTAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTGCGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAATTAACTGATTGGCAACAAAGAATTTCAGATGAACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCACGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCTGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCAGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ATATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACGACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CTAATCATTACCTCTACACAGCGTCAAGTCTCGTTCAGGTTGCAGGCCGGGTCGGCAGGAGTATAGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae Rx1

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae D39

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae R6

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae TIGR4

65.893

100

0.66
  comFA/cflA Streptococcus mitis SK321

65.429

100

0.656
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

37.644

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.349

96.512

0.36

Multiple sequence alignment