Detailed information NTG1128352

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FJH52_RS09510
• Genome accession: NZ_LR595848
• Coordinates: 1889555..1890565 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 4559 isolate 4559
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1884555..1895565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FJH52_RS09485	-	1885901..1886194 (-)	294	WP_000977363.1	hypothetical protein	-
FJH52_RS09490	-	1886356..1886808 (+)	453	WP_000079148.1	universal stress protein	-
FJH52_RS09495	-	1886843..1888231 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
FJH52_RS09500	-	1888297..1889259 (+)	963	WP_001124777.1	asparaginase	-
FJH52_RS09505	-	1889288..1889491 (-)	204	WP_001813553.1	hypothetical protein	-
FJH52_RS09510	ccpA	1889555..1890565 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
FJH52_RS09515	-	1890989..1891588 (-)	600	WP_000866698.1	response regulator transcription factor	-
FJH52_RS09520	-	1891589..1892686 (-)	1098	WP_000893537.1	sensor histidine kinase	-
FJH52_RS09525	-	1892686..1893423 (-)	738	WP_050131518.1	ABC transporter permease	-
FJH52_RS09530	-	1893425..1894309 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
FJH52_RS09535	-	1894296..1894490 (-)	195	WP_000820182.1	hypothetical protein	-
FJH52_RS09540	-	1894487..1894693 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1128352 FJH52_RS09510 WP_000990607.1 1889555..1890565(-) (ccpA) [Streptococcus pneumoniae strain 4559 isolate 4559]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1128352 FJH52_RS09510 WP_000990607.1 1889555..1890565(-) (ccpA) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568